Preservation of resin-dentin interfaces treated with benzalkonium chloride adhesive blends

Camila Sabatini, Pilar A. Ortiz, David H. Pashley

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Reducing collagen degradation within hybrid layers may contribute to the preservation of adhesive interfaces. This study evaluated the stability of resin-dentin interfaces treated with benzalkonium chloride (BAC)-modified adhesive blends and assessed collagen degradation in dentin matrices treated with BAC. The etch-and-rinse adhesive, Adper Single Bond Plus, modified with 0.5% and 1.0% BAC, was evaluated for microtensile bond strength (μTBS) and nanoleakage (NL) after 24 h and 1 yr. Thirty completely demineralized dentin beams from human molars were dipped for 60 s in deionized water (DW; control), or in 0.5% or 1.0% BAC, and then incubated in simulated body fluid (SBF). Collagen degradation was assessed by quantification of the dry mass loss and the amount of hydroxyproline (HYP) released from hydrolyzed specimens after 1 or 4 wk. Although all groups demonstrated a significant increase in NL after 1 yr, adhesive modified with 0.5% BAC showed stable bond strength after 1 yr (9% decrease) relative to the control (44% decrease). Significantly less HYP release and dry mass loss were observed for both 0.5% and 1.0% BAC relative to the control. This in vitro study demonstrates that BAC contributes to the preservation of resin-dentin bonds for up to 1 yr by reducing collagen degradation.

Original languageEnglish (US)
Pages (from-to)108-115
Number of pages8
JournalEuropean Journal of Oral Sciences
Volume123
Issue number2
DOIs
StatePublished - Apr 1 2015

Keywords

  • Benzalkonium chloride
  • Bond strength
  • Dental adhesive
  • Matrix metalloproteinase
  • Proteolysis

ASJC Scopus subject areas

  • Dentistry(all)

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