Abstract
Objective: The purpose of this study was to determine the prevalence of detectable latex-specific IgE in patients being evaluated for allergy. Methods: The AlaSTAT assay was used to test for latex-specific IgE in 200 consecutive serum samples sent to our laboratory for total IgE levels. Samples sent for latex-specific IgE were excluded. The population studied included 87 males and 113 females ranging in age from 1 to 82 years of age. Inhibition studies with a latex extract were performed on all positive samples. Chart reviews and questionnaires provided information regarding risk factors for latex allergy and reactions to latex. Results: Twenty-four (12%) subjects were positive for latex-specific IgE. Seventeen of the 24 positive subjects (70.8%) were <18 years of age and all of the strongly positive subjects (7 or 3.5%) were <18 years of age. The geometric means for total IgE for the latex positive and negative subjects were 351 IU/mL and 80 IU/mL respectively, P < .001. The mean percent inhibition with latex was 66%. Chart reviews and questionnaires revealed only 2 of 24 positive subjects were in high risk groups, none of the positive subjects had any history of reactions to latex, and 22 (91.6%) had evidence of atopic disease. Conclusion: In vitro tests may detect latex specific IgE in atopic individuals, especially children, with no history of recurrent latex exposure and no history of adverse reactions to latex.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 184-187 |
| Number of pages | 4 |
| Journal | Annals of Allergy |
| Volume | 74 |
| Issue number | 2 |
| State | Published - Jan 1 1995 |
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ASJC Scopus subject areas
- Immunology and Allergy
Cite this
Prevalence of latex-specific IgE antibodies in patients being evaluated for allergy. / Reinheimer, G.; Ownby, Dennis Randall.
In: Annals of Allergy, Vol. 74, No. 2, 01.01.1995, p. 184-187.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of latex-specific IgE antibodies in patients being evaluated for allergy
AU - Reinheimer, G.
AU - Ownby, Dennis Randall
PY - 1995/1/1
Y1 - 1995/1/1
N2 - Objective: The purpose of this study was to determine the prevalence of detectable latex-specific IgE in patients being evaluated for allergy. Methods: The AlaSTAT assay was used to test for latex-specific IgE in 200 consecutive serum samples sent to our laboratory for total IgE levels. Samples sent for latex-specific IgE were excluded. The population studied included 87 males and 113 females ranging in age from 1 to 82 years of age. Inhibition studies with a latex extract were performed on all positive samples. Chart reviews and questionnaires provided information regarding risk factors for latex allergy and reactions to latex. Results: Twenty-four (12%) subjects were positive for latex-specific IgE. Seventeen of the 24 positive subjects (70.8%) were <18 years of age and all of the strongly positive subjects (7 or 3.5%) were <18 years of age. The geometric means for total IgE for the latex positive and negative subjects were 351 IU/mL and 80 IU/mL respectively, P < .001. The mean percent inhibition with latex was 66%. Chart reviews and questionnaires revealed only 2 of 24 positive subjects were in high risk groups, none of the positive subjects had any history of reactions to latex, and 22 (91.6%) had evidence of atopic disease. Conclusion: In vitro tests may detect latex specific IgE in atopic individuals, especially children, with no history of recurrent latex exposure and no history of adverse reactions to latex.
AB - Objective: The purpose of this study was to determine the prevalence of detectable latex-specific IgE in patients being evaluated for allergy. Methods: The AlaSTAT assay was used to test for latex-specific IgE in 200 consecutive serum samples sent to our laboratory for total IgE levels. Samples sent for latex-specific IgE were excluded. The population studied included 87 males and 113 females ranging in age from 1 to 82 years of age. Inhibition studies with a latex extract were performed on all positive samples. Chart reviews and questionnaires provided information regarding risk factors for latex allergy and reactions to latex. Results: Twenty-four (12%) subjects were positive for latex-specific IgE. Seventeen of the 24 positive subjects (70.8%) were <18 years of age and all of the strongly positive subjects (7 or 3.5%) were <18 years of age. The geometric means for total IgE for the latex positive and negative subjects were 351 IU/mL and 80 IU/mL respectively, P < .001. The mean percent inhibition with latex was 66%. Chart reviews and questionnaires revealed only 2 of 24 positive subjects were in high risk groups, none of the positive subjects had any history of reactions to latex, and 22 (91.6%) had evidence of atopic disease. Conclusion: In vitro tests may detect latex specific IgE in atopic individuals, especially children, with no history of recurrent latex exposure and no history of adverse reactions to latex.
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M3 - Article
C2 - 7697481
AN - SCOPUS:0028847814
VL - 74
SP - 184
EP - 187
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
SN - 1081-1206
IS - 2
ER -