Prevalence of obstructive sleep apnea in suicidal patients with major depressive disorder

William Vaughn McCall, Ruth M. Benca, Meredith E. Rumble, Doug Case, Peter B. Rosenquist, Andrew D. Krystal

Research output: Contribution to journalArticle

Abstract

In this paper, we report the rate of previously undiagnosed obstructive sleep apnea (OSA) in a randomized clinical trial (RCT) of suicidal patients with major depressive disorder (MDD). One hundred and twenty-five suicidal adults with MDD were recruited into a RCT. None were suspected to have OSA. Fourteen percent met diagnostic criteria for OSA. The Apnea Hypopnea Index (AHI) was predicted by increasing age, male sex, and higher Body Mass Index. However, neither the degree of daytime sleepiness nor the degree of insomnia predicted AHI severity. A high degree of suspicion is warranted for OSA in suicidal patients with MDD, and for patients with treatment-resistant depression. ClinicalTrials.gov identifier: NCT01689909

Original languageEnglish (US)
Pages (from-to)147-150
Number of pages4
JournalJournal of Psychiatric Research
Volume116
DOIs
StatePublished - Sep 1 2019

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Major Depressive Disorder
Obstructive Sleep Apnea
Apnea
Randomized Controlled Trials
Treatment-Resistant Depressive Disorder
Sleep Initiation and Maintenance Disorders
Body Mass Index

Keywords

  • Major depressive disorder
  • Obstructive sleep apnea
  • Suicide
  • Treatment-resistance

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Prevalence of obstructive sleep apnea in suicidal patients with major depressive disorder. / McCall, William Vaughn; Benca, Ruth M.; Rumble, Meredith E.; Case, Doug; Rosenquist, Peter B.; Krystal, Andrew D.

In: Journal of Psychiatric Research, Vol. 116, 01.09.2019, p. 147-150.

Research output: Contribution to journalArticle

McCall, William Vaughn ; Benca, Ruth M. ; Rumble, Meredith E. ; Case, Doug ; Rosenquist, Peter B. ; Krystal, Andrew D. / Prevalence of obstructive sleep apnea in suicidal patients with major depressive disorder. In: Journal of Psychiatric Research. 2019 ; Vol. 116. pp. 147-150.
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