Primary hepatic malignant lymphoma: Its occurrence in a patient with chronic active hepatitis, cirrhosis, and hepatocellular carcinoma associated with hepatitis B viral infection

Thomas S. Talamo, Andrew Dekker, John Gurecki, Gurmukh Singh

Research output: Contribution to journalArticle

77 Scopus citations

Abstract

A patient with hepatitis B induced chronic active hepatitis and cirrhosis had hepatocellular carcinoma and poorly differentiated lymphocytic malignant lymphoma localized in the liver. Whereas a close relationship between hepatitis B viral infection, chronic active hepatitis, macronodular cirrhosis, and hepatocellular carcinoma is now recognized, no such association has been reported with primary hepatic malignant lymphoma, which is a distinctly rare entity. In a large autopsy population that we reviewed, systemic malignant lymphoma rarely occurred in association with cirrhosis. Such an association has been noted in other studies, however. We speculate that if an association exists between malignant lymphoma and cirrhosis it might have an immunologic basis such as seen in certain autoimmune diseases.

Original languageEnglish (US)
Pages (from-to)336-339
Number of pages4
JournalCancer
Volume46
Issue number2
DOIs
StatePublished - Jul 15 1980
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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