TY - JOUR
T1 - Primary hepatic malignant lymphoma
T2 - Its occurrence in a patient with chronic active hepatitis, cirrhosis, and hepatocellular carcinoma associated with hepatitis B viral infection
AU - Talamo, Thomas S.
AU - Dekker, Andrew
AU - Gurecki, John
AU - Singh, Gurmukh
PY - 1980/7/15
Y1 - 1980/7/15
N2 - A patient with hepatitis B induced chronic active hepatitis and cirrhosis had hepatocellular carcinoma and poorly differentiated lymphocytic malignant lymphoma localized in the liver. Whereas a close relationship between hepatitis B viral infection, chronic active hepatitis, macronodular cirrhosis, and hepatocellular carcinoma is now recognized, no such association has been reported with primary hepatic malignant lymphoma, which is a distinctly rare entity. In a large autopsy population that we reviewed, systemic malignant lymphoma rarely occurred in association with cirrhosis. Such an association has been noted in other studies, however. We speculate that if an association exists between malignant lymphoma and cirrhosis it might have an immunologic basis such as seen in certain autoimmune diseases.
AB - A patient with hepatitis B induced chronic active hepatitis and cirrhosis had hepatocellular carcinoma and poorly differentiated lymphocytic malignant lymphoma localized in the liver. Whereas a close relationship between hepatitis B viral infection, chronic active hepatitis, macronodular cirrhosis, and hepatocellular carcinoma is now recognized, no such association has been reported with primary hepatic malignant lymphoma, which is a distinctly rare entity. In a large autopsy population that we reviewed, systemic malignant lymphoma rarely occurred in association with cirrhosis. Such an association has been noted in other studies, however. We speculate that if an association exists between malignant lymphoma and cirrhosis it might have an immunologic basis such as seen in certain autoimmune diseases.
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U2 - 10.1002/1097-0142(19800715)46:2<336::AID-CNCR2820460221>3.0.CO;2-1
DO - 10.1002/1097-0142(19800715)46:2<336::AID-CNCR2820460221>3.0.CO;2-1
M3 - Article
C2 - 6248191
AN - SCOPUS:0018899103
SN - 0008-543X
VL - 46
SP - 336
EP - 339
JO - Cancer
JF - Cancer
IS - 2
ER -