Primary intramedullary primitive neuroectodermal tumor of the cervical spinal cord

Case report

Amit Jain, Rakesh Jalali, Trimurti D. Nadkarni, Suash Sharma

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Primary intramedullary primitive neuroectodermal tumors (PNETs) of the spinal cord are rare. Only six cases have previously been reported, all involving tumors in the thoracic or lumbar spine. The authors report the case of a 54-year-old woman who presented with quadriplegia and bladder and bowel dysfunction. The patient had suffered symptoms of neck pain for 1 month and left shoulder weakness for 10 days. Magnetic resonance imaging of the cervical spine revealed an intramedullary mass extending from C-2 to C-5 with an exophytic component in the adjacent left subarachnoid space. Multiple biopsy specimens were obtained, and a partial excision was performed. Histological examination revealed nodular growth and neuronal differentiation, with a striking resemblance to desmoplastic medulloblastoma. A positron emission tomography scan did not reveal uptake at any site. These findings confirmed the diagnosis of a primary intramedullary PNET. Postoperatively, the patient was given craniospinal radiotherapy with a radiation boost to the tumor bed.

Original languageEnglish (US)
Pages (from-to)497-502
Number of pages6
JournalJournal of Neurosurgery: Spine
Volume4
Issue number6
DOIs
StatePublished - Jun 1 2006
Externally publishedYes

Fingerprint

Primitive Neuroectodermal Tumors
Spine
Subarachnoid Space
Medulloblastoma
Quadriplegia
Neck Pain
Positron-Emission Tomography
Neoplasms
Spinal Cord
Urinary Bladder
Radiotherapy
Thorax
Magnetic Resonance Imaging
Radiation
Biopsy
Growth
Cervical Cord

Keywords

  • Intramedullary tumor
  • Primitive neuroectodermal tumor
  • Spinal cord neoplasm

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology

Cite this

Primary intramedullary primitive neuroectodermal tumor of the cervical spinal cord : Case report. / Jain, Amit; Jalali, Rakesh; Nadkarni, Trimurti D.; Sharma, Suash.

In: Journal of Neurosurgery: Spine, Vol. 4, No. 6, 01.06.2006, p. 497-502.

Research output: Contribution to journalArticle

Jain, Amit ; Jalali, Rakesh ; Nadkarni, Trimurti D. ; Sharma, Suash. / Primary intramedullary primitive neuroectodermal tumor of the cervical spinal cord : Case report. In: Journal of Neurosurgery: Spine. 2006 ; Vol. 4, No. 6. pp. 497-502.
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