Abstract
A 64-yr-old female developed acute myeloblastic leukemia following radiation and drug therapy for colon carcinoma. The patient was heterozygous for glucose-6-phosphate dehydrogenase (G-6-PD) and displayed types A and B isoenzymes in nonhematopoietic tissue. In contrast, only type B G-6-PD was observed in peripheral blood white cells. In addition, a karyotypic abnormality was found in peripheral blood and marrow cells but not in skin fibroblasts. The data are consistent with a clonal origin of this leukemia.
Original language | English (US) |
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Pages (from-to) | 659-663 |
Number of pages | 5 |
Journal | Blood |
Volume | 52 |
Issue number | 4 |
State | Published - Dec 1 1978 |
ASJC Scopus subject areas
- Hematology