Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis

Viswanath P. Kurup, Raghavan Pillai Raju, Pachiappan Manickam

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the Aspergillus allergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed enhanced expression and represent chemokine, cytokine, growth factor, signal transduction, and transmembrane receptor genes as well as genes related to arginine metabolism.

Original languageEnglish (US)
Pages (from-to)4381-4384
Number of pages4
JournalInfection and Immunity
Volume73
Issue number7
DOIs
StatePublished - Jul 1 2005

Fingerprint

Allergic Bronchopulmonary Aspergillosis
Transcriptome
Genes
Aspergillus
Chemokines
Allergens
Arginine
Immune System
Signal Transduction
Intercellular Signaling Peptides and Proteins
Cytokines

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

Cite this

Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis. / Kurup, Viswanath P.; Raju, Raghavan Pillai; Manickam, Pachiappan.

In: Infection and Immunity, Vol. 73, No. 7, 01.07.2005, p. 4381-4384.

Research output: Contribution to journalArticle

Kurup, Viswanath P. ; Raju, Raghavan Pillai ; Manickam, Pachiappan. / Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis. In: Infection and Immunity. 2005 ; Vol. 73, No. 7. pp. 4381-4384.
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