Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis

Viswanath P. Kurup, Raghavan Raju, Pachiappan Manickam

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the Aspergillus allergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showed enhanced expression and represent chemokine, cytokine, growth factor, signal transduction, and transmembrane receptor genes as well as genes related to arginine metabolism.

Original languageEnglish (US)
Pages (from-to)4381-4384
Number of pages4
JournalInfection and Immunity
Volume73
Issue number7
DOIs
StatePublished - Jul 2005
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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