Protein tyrosine kinases and phosphatases in the nervous system

Kathryn R. Wagner; Lin Mei; Richard L. Huganir

doi:10.1016/0959-4388(91)90011-U

Protein tyrosine kinases and phosphatases in the nervous system

Kathryn R. Wagner, Lin Mei, Richard L. Huganir

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Evidence in the past year has provided support for a prominent role of tyrosine phosphorylation in the regulation of neuronal function. The discovery that many novel forms of protein tyrosine kinases and phosphatases are expressed in the brain has revealed that the regulation of tyrosine phosphorylation is highly complex. The recent identification of substrate proteins in the brain for the protein tyrosine kinases and phosphatases has begun to clarify the functional role of tyrosine phosphorylation in the development and modulation of the nervous system.

Original language	English (US)
Pages (from-to)	65-73
Number of pages	9
Journal	Current Opinion in Neurobiology
Volume	1
Issue number	1
DOIs	https://doi.org/10.1016/0959-4388(91)90011-U
State	Published - Jun 1991
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

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10.1016/0959-4388(91)90011-U

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title = "Protein tyrosine kinases and phosphatases in the nervous system",

abstract = "Evidence in the past year has provided support for a prominent role of tyrosine phosphorylation in the regulation of neuronal function. The discovery that many novel forms of protein tyrosine kinases and phosphatases are expressed in the brain has revealed that the regulation of tyrosine phosphorylation is highly complex. The recent identification of substrate proteins in the brain for the protein tyrosine kinases and phosphatases has begun to clarify the functional role of tyrosine phosphorylation in the development and modulation of the nervous system.",

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year = "1991",

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AB - Evidence in the past year has provided support for a prominent role of tyrosine phosphorylation in the regulation of neuronal function. The discovery that many novel forms of protein tyrosine kinases and phosphatases are expressed in the brain has revealed that the regulation of tyrosine phosphorylation is highly complex. The recent identification of substrate proteins in the brain for the protein tyrosine kinases and phosphatases has begun to clarify the functional role of tyrosine phosphorylation in the development and modulation of the nervous system.

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Protein tyrosine kinases and phosphatases in the nervous system

Abstract

ASJC Scopus subject areas

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