Pseudocholinesterase deficiency and electroconvulsive therapy

Joseph Williams, Peter B. Rosenquist, Lorraine Arias, William Vaughn McCall

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Clinically significant pseudocholinesterase deficiency is a relatively uncommon disorder, but when present, it presents clinicians with challenges regarding medication administration. This is especially true in cases of patients receiving electroconvulsive therapy (ECT), as the presence of pseudocholinesterase deficiency limits the use of certain muscle relaxants. The authors describe a patient receiving ECT for treatment of his depression, who also possessed an unsuspected pseudocholinesterase deficiency. This was diagnosed after the patient was given succinylcholine, did not spontaneously recover motor function, and eventually required intubation. Subsequent ECT treatments were then managed with an alternative muscle relaxant which was not dependent on pseudocholinesterase for termination of action.

Original languageEnglish (US)
Pages (from-to)198-200
Number of pages3
JournalJournal of ECT
Volume23
Issue number3
DOIs
StatePublished - Sep 1 2007

Fingerprint

Electroconvulsive Therapy
Pseudocholinesterase
Muscles
Succinylcholine
Intubation
Depression
Therapeutics
Butyrylcholinesterase deficiency

Keywords

  • Cholinesterase
  • ECT
  • Electroconvulsive therapy
  • Pseudocholinesterase
  • Pseudocholinesterase deficiency
  • Rocuronium
  • Succinylcholine

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Psychiatry and Mental health

Cite this

Pseudocholinesterase deficiency and electroconvulsive therapy. / Williams, Joseph; Rosenquist, Peter B.; Arias, Lorraine; McCall, William Vaughn.

In: Journal of ECT, Vol. 23, No. 3, 01.09.2007, p. 198-200.

Research output: Contribution to journalArticle

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