Ptp1b deletion in pro-opiomelanocortin neurons increases energy expenditure and impairs endothelial function via TNF-α dependent mechanisms

Medicine & Life Sciences

• Non-Receptor Type 1 Protein Tyrosine Phosphatase 100%
• Pro-Opiomelanocortin 84%
• Energy Metabolism 59%
• Tumor Necrosis Factor-alpha 46%
• Neurons 40%
• NADPH Oxidase 2 14%
• Etanercept 11%
• Body Temperature 9%
• Superoxide Dismutase 8%
• Body Weight 6%
• arginine methyl ester 5%
• Thromboxane A2 5%
• Tumor Necrosis Factor Receptors 5%
• NADPH Oxidases 5%
• NG-Nitroarginine Methyl Ester 5%
• Enzymes 5%
• Cyclooxygenase 2 4%
• Leptin 4%
• Oxygen Consumption 4%
• Nitric Oxide Synthase 4%
• Weight Gain 4%
• Aorta 4%
• Adipose Tissue 3%
• Obesity 3%
• Insulin 3%
• Phenotype 2%
• Inflammation 2%
• Blood Vessels 2%