Pulse oximetry correction for smoking exposure

Kevin L. Glass, Thomas A Dillard, Yancy Y. Phillips, Kenneth G. Torrington, Jennifer C. Thompson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Pulse oximetry oxygen saturation (SpO2) does not distinguish carboxyhemoglobin (COHb) from oxyhemoglobin (O2Hb), giving a false impression of the apparent degree of oxyhemoglobin saturation in smokers who have elevated levels of COHb. We questioned whether accounting for smoking exposure history could improve description of pulse oximetry by correcting for COHb levels. We evaluated smoking history and %SpO2 as predictors of %O2Hb and %COHb by CO-oximetry of arterial blood in 18 actively smoking and 18 age-matched nonsmoking patients in a clinical pilot study. The difference between %SpO2 and %O2Hb was significantly greater (p < 0.001) in the smokers (5.6 ± 3.1) than the nonsmokers (2.1 ± 2.1). This difference correlated with %COHb (r(p) = 0.789; p < 0.001) and the smoking exposure score (SES, r(p) = 0.621; p < 0.001), a six-point index we developed based on whether patients were active smokers, refrained from smoking prior to testing, or were exposed to passive smoking in the home or workplace. The following formula summarizes the correction: %O2Hb = 0.882[%SpO2] - 0.968[SES] + 9.245 (r(p) = 0.841; SES = 2.478; p < 0.001). This pilot study suggests that smoking exposure history correlates with COHb levels and that correction for smoking exposure improves the accuracy of pulse oximetry.

Original languageEnglish (US)
Pages (from-to)273-276
Number of pages4
JournalMilitary medicine
Volume161
Issue number5
StatePublished - May 29 1996

Fingerprint

Oximetry
Carboxyhemoglobin
Smoking
Oxyhemoglobins
History
Tobacco Smoke Pollution
Carbon Monoxide
Workplace
Oxygen

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Glass, K. L., Dillard, T. A., Phillips, Y. Y., Torrington, K. G., & Thompson, J. C. (1996). Pulse oximetry correction for smoking exposure. Military medicine, 161(5), 273-276.

Pulse oximetry correction for smoking exposure. / Glass, Kevin L.; Dillard, Thomas A; Phillips, Yancy Y.; Torrington, Kenneth G.; Thompson, Jennifer C.

In: Military medicine, Vol. 161, No. 5, 29.05.1996, p. 273-276.

Research output: Contribution to journalArticle

Glass, KL, Dillard, TA, Phillips, YY, Torrington, KG & Thompson, JC 1996, 'Pulse oximetry correction for smoking exposure', Military medicine, vol. 161, no. 5, pp. 273-276.
Glass KL, Dillard TA, Phillips YY, Torrington KG, Thompson JC. Pulse oximetry correction for smoking exposure. Military medicine. 1996 May 29;161(5):273-276.
Glass, Kevin L. ; Dillard, Thomas A ; Phillips, Yancy Y. ; Torrington, Kenneth G. ; Thompson, Jennifer C. / Pulse oximetry correction for smoking exposure. In: Military medicine. 1996 ; Vol. 161, No. 5. pp. 273-276.
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