Abstract
Pulse wave velocity (PWV) has been used as a measurement for arterial stiffness, a predictor of cardiovascular risk. Tracking describes the stability of a measurement over time. The purpose of this study was to evaluate the tracking stability of carotid-femoral (cfPWV), carotid-radial (crPWV) and carotid-distal (cdPWV) PWV in young adults and their associations with anthropometric and hemodynamic measurements. cfPWV, crPWV and cdPWV were measured by tonometric (SphygmoCor) technique in 531 subjects (aged 23.7±4.9 with 42.9% African Americans and 49.9% females). Out of these subjects, 142 subjects had all these 3 PWV measurements evaluated again during their next visit with an average follow-up time of 2 years. In the tracking analysis on the data from the 142 subjects, cfPWV displayed moderate to relatively high tracking ability (r=0.61, P<0.001), whereas crPWV and cdPWV only displayed low to moderate tracking coefficients (r=0.29 and r=0.36 respectively, P<0.001). In the association test on the data from the 531 subjects, all three PWV measurements showed significant correlations with age and obesity related measurements. cfPWV displayed stronger correlations with these parameters. In addition, all three PWVs showed significant correlations with systolic blood pressure, diastolic blood pressure, mean arterial pressure and pulse pressure with the exception that no correlation existed between crPWV and pulse pressure. The higher tracking ability of cfPWV and its higher association with obesity related measurements highlights the importance of using cfPWV compared with crPWV and cdPWV for research and clinical settings.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 786-791 |
| Number of pages | 6 |
| Journal | Hypertension Research |
| Volume | 39 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 2016 |
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Keywords
- arterial stiffness
- longitudinal study
- pulse wave velocity
- tracking
ASJC Scopus subject areas
- Internal Medicine
- Physiology
- Cardiology and Cardiovascular Medicine
Cite this
Pulse wave velocity in elastic and muscular arteries : Tracking stability and association with anthropometric and hemodynamic measurements. / Ye, Chengcheng; Pan, Yue; Xu, Xiaojing; Su, Shaoyong; Snieder, Harold; Treiber, Frank; Kapuku, Gaston; Wang, Xiaoling.
In: Hypertension Research, Vol. 39, No. 11, 01.11.2016, p. 786-791.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pulse wave velocity in elastic and muscular arteries
T2 - Tracking stability and association with anthropometric and hemodynamic measurements
AU - Ye, Chengcheng
AU - Pan, Yue
AU - Xu, Xiaojing
AU - Su, Shaoyong
AU - Snieder, Harold
AU - Treiber, Frank
AU - Kapuku, Gaston
AU - Wang, Xiaoling
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Pulse wave velocity (PWV) has been used as a measurement for arterial stiffness, a predictor of cardiovascular risk. Tracking describes the stability of a measurement over time. The purpose of this study was to evaluate the tracking stability of carotid-femoral (cfPWV), carotid-radial (crPWV) and carotid-distal (cdPWV) PWV in young adults and their associations with anthropometric and hemodynamic measurements. cfPWV, crPWV and cdPWV were measured by tonometric (SphygmoCor) technique in 531 subjects (aged 23.7±4.9 with 42.9% African Americans and 49.9% females). Out of these subjects, 142 subjects had all these 3 PWV measurements evaluated again during their next visit with an average follow-up time of 2 years. In the tracking analysis on the data from the 142 subjects, cfPWV displayed moderate to relatively high tracking ability (r=0.61, P<0.001), whereas crPWV and cdPWV only displayed low to moderate tracking coefficients (r=0.29 and r=0.36 respectively, P<0.001). In the association test on the data from the 531 subjects, all three PWV measurements showed significant correlations with age and obesity related measurements. cfPWV displayed stronger correlations with these parameters. In addition, all three PWVs showed significant correlations with systolic blood pressure, diastolic blood pressure, mean arterial pressure and pulse pressure with the exception that no correlation existed between crPWV and pulse pressure. The higher tracking ability of cfPWV and its higher association with obesity related measurements highlights the importance of using cfPWV compared with crPWV and cdPWV for research and clinical settings.
AB - Pulse wave velocity (PWV) has been used as a measurement for arterial stiffness, a predictor of cardiovascular risk. Tracking describes the stability of a measurement over time. The purpose of this study was to evaluate the tracking stability of carotid-femoral (cfPWV), carotid-radial (crPWV) and carotid-distal (cdPWV) PWV in young adults and their associations with anthropometric and hemodynamic measurements. cfPWV, crPWV and cdPWV were measured by tonometric (SphygmoCor) technique in 531 subjects (aged 23.7±4.9 with 42.9% African Americans and 49.9% females). Out of these subjects, 142 subjects had all these 3 PWV measurements evaluated again during their next visit with an average follow-up time of 2 years. In the tracking analysis on the data from the 142 subjects, cfPWV displayed moderate to relatively high tracking ability (r=0.61, P<0.001), whereas crPWV and cdPWV only displayed low to moderate tracking coefficients (r=0.29 and r=0.36 respectively, P<0.001). In the association test on the data from the 531 subjects, all three PWV measurements showed significant correlations with age and obesity related measurements. cfPWV displayed stronger correlations with these parameters. In addition, all three PWVs showed significant correlations with systolic blood pressure, diastolic blood pressure, mean arterial pressure and pulse pressure with the exception that no correlation existed between crPWV and pulse pressure. The higher tracking ability of cfPWV and its higher association with obesity related measurements highlights the importance of using cfPWV compared with crPWV and cdPWV for research and clinical settings.
KW - arterial stiffness
KW - longitudinal study
KW - pulse wave velocity
KW - tracking
UR - http://www.scopus.com/inward/record.url?scp=84994718545&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84994718545&partnerID=8YFLogxK
U2 - 10.1038/hr.2016.67
DO - 10.1038/hr.2016.67
M3 - Article
C2 - 27334066
AN - SCOPUS:84994718545
VL - 39
SP - 786
EP - 791
JO - Hypertension Research
JF - Hypertension Research
SN - 0916-9636
IS - 11
ER -