Quantitative estimation of the recurrent laryngeal nerve irritation by employing spontaneous intraoperative electromyographic monitoring during anterior cervical discectomy and fusion

Vasilios G. Dimopoulos, Induk Chung, Gregory P Lee, Kim W. Johnston, Ioannis Z. Kapsalakis, Hugh F. Smisson, Arthur A. Grigorian, Joe S. Robinson, Kostas N. Fountas

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

STUDY DESIGN: Prospective, clinical study. OBJECTIVE: The objective of our study was to evaluate the role of laryngeal intraoperative electromyography (IEMG) in predicting the development of postoperative recurrent laryngeal nerve (RLN) palsy in patients undergoing anterior cervical discectomy and fusion (ACDF). We also attempted to develop a method to quantify the total IEMG irritation of the RLN. SUMMARY OF BACKGROUND DATA: RLN injury has been recognized as the most common ACDF-associated neurologic injury. It has been postulated, that the employment of laryngeal IEMG may identify the operative events leading to RLN injury and subsequent postoperative palsy. METHODS: Laryngeal IEMG monitoring was performed in 298 patients undergoing ACDF. Preexistent baseline EMG activity, amplitude, and duration of IEMG activity were recorded. The total amount of RLN irritation was expressed as an Irritation Score (IS) applying a specially designed mathematical equation incorporating the amplitude, the duration, and the presence of any baseline EMG irritation. The relationship of IEMG activity with parameters such as the number of operative levels, the duration of the procedure, the presence of any previous neck surgeries, and the type of the used retractor was examined. RESULTS: IEMG activity was recorded in 14.4% of our patients. Postoperative RLN injury occurred in 2.3% of our patients. The sensitivity of IEMG was 100%, the specificity 87%, the positive predictive value 16%, and its negative predictive value 97%. The calculated IS ranged between 0.28 and 3.47 (mean IS: 2.09). Significantly increased IEMG activity was found in patients with previous surgical intervention, patients undergoing multilevel procedures, long-lasting procedures, and cases in which self-retained retractors were used. Likewise, significantly increased IS were observed in patients with previous surgeries and in cases where self-retained retractors were used. CONCLUSIONS: Our study indicates that laryngeal IEMG is a high-sensitivity modality that can provide real-time information and can potentially minimize the risk of operative RLN injury.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalJournal of Spinal Disorders and Techniques
Volume22
Issue number1
DOIs
StatePublished - Feb 1 2009

Fingerprint

Intraoperative Monitoring
Recurrent Laryngeal Nerve
Diskectomy
Electromyography
Recurrent Laryngeal Nerve Injuries
Nervous System Trauma
Vocal Cord Paralysis
Paralysis
Neck
Prospective Studies

Keywords

  • Anterior cervical discectomy
  • Electromyography
  • Injury
  • Irritation
  • Recurrent laryngeal nerve
  • Vocal cord

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology

Cite this

Quantitative estimation of the recurrent laryngeal nerve irritation by employing spontaneous intraoperative electromyographic monitoring during anterior cervical discectomy and fusion. / Dimopoulos, Vasilios G.; Chung, Induk; Lee, Gregory P; Johnston, Kim W.; Kapsalakis, Ioannis Z.; Smisson, Hugh F.; Grigorian, Arthur A.; Robinson, Joe S.; Fountas, Kostas N.

In: Journal of Spinal Disorders and Techniques, Vol. 22, No. 1, 01.02.2009, p. 1-7.

Research output: Contribution to journalArticle

Dimopoulos, Vasilios G. ; Chung, Induk ; Lee, Gregory P ; Johnston, Kim W. ; Kapsalakis, Ioannis Z. ; Smisson, Hugh F. ; Grigorian, Arthur A. ; Robinson, Joe S. ; Fountas, Kostas N. / Quantitative estimation of the recurrent laryngeal nerve irritation by employing spontaneous intraoperative electromyographic monitoring during anterior cervical discectomy and fusion. In: Journal of Spinal Disorders and Techniques. 2009 ; Vol. 22, No. 1. pp. 1-7.
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abstract = "STUDY DESIGN: Prospective, clinical study. OBJECTIVE: The objective of our study was to evaluate the role of laryngeal intraoperative electromyography (IEMG) in predicting the development of postoperative recurrent laryngeal nerve (RLN) palsy in patients undergoing anterior cervical discectomy and fusion (ACDF). We also attempted to develop a method to quantify the total IEMG irritation of the RLN. SUMMARY OF BACKGROUND DATA: RLN injury has been recognized as the most common ACDF-associated neurologic injury. It has been postulated, that the employment of laryngeal IEMG may identify the operative events leading to RLN injury and subsequent postoperative palsy. METHODS: Laryngeal IEMG monitoring was performed in 298 patients undergoing ACDF. Preexistent baseline EMG activity, amplitude, and duration of IEMG activity were recorded. The total amount of RLN irritation was expressed as an Irritation Score (IS) applying a specially designed mathematical equation incorporating the amplitude, the duration, and the presence of any baseline EMG irritation. The relationship of IEMG activity with parameters such as the number of operative levels, the duration of the procedure, the presence of any previous neck surgeries, and the type of the used retractor was examined. RESULTS: IEMG activity was recorded in 14.4{\%} of our patients. Postoperative RLN injury occurred in 2.3{\%} of our patients. The sensitivity of IEMG was 100{\%}, the specificity 87{\%}, the positive predictive value 16{\%}, and its negative predictive value 97{\%}. The calculated IS ranged between 0.28 and 3.47 (mean IS: 2.09). Significantly increased IEMG activity was found in patients with previous surgical intervention, patients undergoing multilevel procedures, long-lasting procedures, and cases in which self-retained retractors were used. Likewise, significantly increased IS were observed in patients with previous surgeries and in cases where self-retained retractors were used. CONCLUSIONS: Our study indicates that laryngeal IEMG is a high-sensitivity modality that can provide real-time information and can potentially minimize the risk of operative RLN injury.",
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AU - Lee, Gregory P

AU - Johnston, Kim W.

AU - Kapsalakis, Ioannis Z.

AU - Smisson, Hugh F.

AU - Grigorian, Arthur A.

AU - Robinson, Joe S.

AU - Fountas, Kostas N.

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N2 - STUDY DESIGN: Prospective, clinical study. OBJECTIVE: The objective of our study was to evaluate the role of laryngeal intraoperative electromyography (IEMG) in predicting the development of postoperative recurrent laryngeal nerve (RLN) palsy in patients undergoing anterior cervical discectomy and fusion (ACDF). We also attempted to develop a method to quantify the total IEMG irritation of the RLN. SUMMARY OF BACKGROUND DATA: RLN injury has been recognized as the most common ACDF-associated neurologic injury. It has been postulated, that the employment of laryngeal IEMG may identify the operative events leading to RLN injury and subsequent postoperative palsy. METHODS: Laryngeal IEMG monitoring was performed in 298 patients undergoing ACDF. Preexistent baseline EMG activity, amplitude, and duration of IEMG activity were recorded. The total amount of RLN irritation was expressed as an Irritation Score (IS) applying a specially designed mathematical equation incorporating the amplitude, the duration, and the presence of any baseline EMG irritation. The relationship of IEMG activity with parameters such as the number of operative levels, the duration of the procedure, the presence of any previous neck surgeries, and the type of the used retractor was examined. RESULTS: IEMG activity was recorded in 14.4% of our patients. Postoperative RLN injury occurred in 2.3% of our patients. The sensitivity of IEMG was 100%, the specificity 87%, the positive predictive value 16%, and its negative predictive value 97%. The calculated IS ranged between 0.28 and 3.47 (mean IS: 2.09). Significantly increased IEMG activity was found in patients with previous surgical intervention, patients undergoing multilevel procedures, long-lasting procedures, and cases in which self-retained retractors were used. Likewise, significantly increased IS were observed in patients with previous surgeries and in cases where self-retained retractors were used. CONCLUSIONS: Our study indicates that laryngeal IEMG is a high-sensitivity modality that can provide real-time information and can potentially minimize the risk of operative RLN injury.

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KW - Electromyography

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KW - Irritation

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