Abstract
Lung tissues from 32 cases of lung cancer with surgical operation, 22 smokers and 10 nonsmokers, were analyzed with P1-mediated modification of 32P-postlabelling technique. The level of lung DNA-adduct in cigarette smokers was higher that in nonsmokers with significant difference (P < 0.001). Autoradiogram showed a diagonal radioactive zone in smokers' lung tissues. Correlation analysis indicated DNA-adduct in lung tissues increased with the number of cigarettes smoked with a regression equation of Y = 0.411 X + 3.52, r = 0.74, P < 0.001.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 206-209 |
| Number of pages | 4 |
| Journal | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] |
| Volume | 28 |
| Issue number | 4 |
| State | Published - Jul 1994 |
| Externally published | Yes |
ASJC Scopus subject areas
- General Medicine
