Quinidine-induced thrombocytopenia successfully treated with plasma exchange

T. H. Guthrie, Christophe Pallas, J. E. Squires

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 66-year-old woman had significant cervical, oral, and gastrointestinal bleeding associated with quindine-induced immune thrombocytopenia. No response to discontinuance of quinidine, high dose steroids, or platelet transfusion was noted after three days of observation. A single plasma exchange induced immediate cessation of bleeding and rapid restoration of a normal platelet count. Plasma exchange would appear to warrant further exploration in the management of drug-induced thrombocytopenia when the offending drug is heavily bound to plasma proteins.

Original languageEnglish (US)
Pages (from-to)361-363
Number of pages3
JournalPlasma Therapy and Transfusion Technology
Volume5
Issue number3
StatePublished - Jan 1 1984

Fingerprint

Plasma Exchange
Quinidine
Thrombocytopenia
Hemorrhage
Platelet Transfusion
Idiopathic Thrombocytopenic Purpura
Platelet Count
Pharmaceutical Preparations
Blood Proteins
Steroids
Observation

ASJC Scopus subject areas

  • Immunology
  • Hematology

Cite this

Quinidine-induced thrombocytopenia successfully treated with plasma exchange. / Guthrie, T. H.; Pallas, Christophe; Squires, J. E.

In: Plasma Therapy and Transfusion Technology, Vol. 5, No. 3, 01.01.1984, p. 361-363.

Research output: Contribution to journalArticle

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