Racial differences in the age-related increase in left ventricular mass in youths

Gregory A. Harshfield, David W. Koelsch, Derrick A. Pulliam, Bruce S. Alpert, Phyllis A. Richey, Judith A. Becker

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

We determined the factors related to left ventricular mass adjusted for body size in 60 black (mean age, 13±2 years) and 40 white (mean age, 14±2 years) normotensive youths. The factors examined included age, sex, systolic blood pressure, diastolic blood pressure, plasma renin activity, plasma aldosterone concentration, and sodium and potassium intake as determined by 24-hour excretion. Sex (β=13.3, P<.003), age (β=2.88, P<.001), and systolic blood pressure (β=0.41, P<.02) were independent predictors in the sample as a whole, accounting for 37% of the variance of left ventricular mass adjusted for height. Separate analyses were performed for black and white subjects. In the black subjects, age (β=4.4, P<.004) followed by sex (β=11.85, P<.02) were independent factors, accounting for 43% of the variance of left ventricular mass adjusted for height. In contrast, in white subjects systolic blood pressure (β=0.4, P<.003) followed by sodium excretion (β=0.13, P<.05) were independent factors, with gender (β=8.89, P<.07) tending to account for 36% of the variance. Similar results were observed for left ventricular mass adjusted for body surface area. In conclusion, the age-related increase in adjusted left ventricular mass in black but not white youths may in part account for the early development of cardiovascular disease among the black population.

Original languageEnglish (US)
Pages (from-to)747-751
Number of pages5
JournalHypertension
Volume24
Issue number6
DOIs
StatePublished - Dec 1994
Externally publishedYes

Keywords

  • blood pressure
  • left ventricular mass
  • racial differences
  • sex differences
  • sodium excretion

ASJC Scopus subject areas

  • Internal Medicine

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  • Cite this

    Harshfield, G. A., Koelsch, D. W., Pulliam, D. A., Alpert, B. S., Richey, P. A., & Becker, J. A. (1994). Racial differences in the age-related increase in left ventricular mass in youths. Hypertension, 24(6), 747-751. https://doi.org/10.1161/01.HYP.24.6.747