Radium in Wisconsin Drinking Water: An Analysis of Osteosarcoma Risk

Clare E. Guse, Anne M. Marbella, Varghese George, Peter M. Layde

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.

Original languageEnglish (US)
Pages (from-to)294-303
Number of pages10
JournalArchives of Environmental Health
Volume57
Issue number4
DOIs
StatePublished - Jul 1 2002
Externally publishedYes

Fingerprint

Water analysis
Radium
radium
Osteosarcoma
Drinking Water
drinking water
Association reactions
Bone Neoplasms
water analysis
confidence interval
Case-Control Studies
Epidemiologic Studies
bone
cancer
Bone
Odds Ratio
Confidence Intervals

Keywords

  • Drinking water
  • Osteosarcoma
  • Radium

ASJC Scopus subject areas

  • Environmental Chemistry
  • Environmental Science(all)
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Radium in Wisconsin Drinking Water : An Analysis of Osteosarcoma Risk. / Guse, Clare E.; Marbella, Anne M.; George, Varghese; Layde, Peter M.

In: Archives of Environmental Health, Vol. 57, No. 4, 01.07.2002, p. 294-303.

Research output: Contribution to journalArticle

Guse, Clare E. ; Marbella, Anne M. ; George, Varghese ; Layde, Peter M. / Radium in Wisconsin Drinking Water : An Analysis of Osteosarcoma Risk. In: Archives of Environmental Health. 2002 ; Vol. 57, No. 4. pp. 294-303.
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