Reaction of barbituric acid with organic azides and phosphonium ylides

Iryna Oleksandrivna Lebedyeva, Sean M. Sileno, Kunal Patel, Ion Ghiviriga, Peter J. Steel, Alan R. Katritzky

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Amination by organic azides has been carried out to provide aminobarbiturates by fusion of a triazole ring to the 5,6-positions of barbituric acid followed by cleavage and thermal elimination of nitrogen, whereas aza-Wittig reaction gave phosphoranylidene barbituric acid salts.

    Original languageEnglish (US)
    Pages (from-to)1019-1022
    Number of pages4
    JournalCentral European Journal of Chemistry
    Volume11
    Issue number6
    DOIs
    StatePublished - 2013

    Keywords

    • Aza-Wittig reaction
    • Azide
    • Barbiturate
    • Pyrimidine

    ASJC Scopus subject areas

    • General Chemistry
    • Materials Chemistry

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