Reaction of barbituric acid with organic azides and phosphonium ylides

Iryna Oleksandrivna Lebedyeva, Sean M. Sileno, Kunal Patel, Ion Ghiviriga, Peter J. Steel, Alan R. Katritzky

Research output: Contribution to journalArticle

Abstract

Amination by organic azides has been carried out to provide aminobarbiturates by fusion of a triazole ring to the 5,6-positions of barbituric acid followed by cleavage and thermal elimination of nitrogen, whereas aza-Wittig reaction gave phosphoranylidene barbituric acid salts.

Original languageEnglish (US)
Pages (from-to)1019-1022
Number of pages4
JournalCentral European Journal of Chemistry
Volume11
Issue number6
DOIs
StatePublished - Dec 1 2013

Fingerprint

Azides
Amination
Triazoles
Acids
Nitrogen
Fusion reactions
Salts
barbituric acid
Hot Temperature

Keywords

  • Aza-Wittig reaction
  • Azide
  • Barbiturate
  • Pyrimidine

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

Cite this

Reaction of barbituric acid with organic azides and phosphonium ylides. / Lebedyeva, Iryna Oleksandrivna; Sileno, Sean M.; Patel, Kunal; Ghiviriga, Ion; Steel, Peter J.; Katritzky, Alan R.

In: Central European Journal of Chemistry, Vol. 11, No. 6, 01.12.2013, p. 1019-1022.

Research output: Contribution to journalArticle

Lebedyeva, Iryna Oleksandrivna ; Sileno, Sean M. ; Patel, Kunal ; Ghiviriga, Ion ; Steel, Peter J. ; Katritzky, Alan R. / Reaction of barbituric acid with organic azides and phosphonium ylides. In: Central European Journal of Chemistry. 2013 ; Vol. 11, No. 6. pp. 1019-1022.
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