Reaction of barbituric acid with organic azides and phosphonium ylides

Iryna Oleksandrivna Lebedyeva, Sean M. Sileno, Kunal Patel, Ion Ghiviriga, Peter J. Steel, Alan R. Katritzky

Research output: Contribution to journalArticle

Abstract

Amination by organic azides has been carried out to provide aminobarbiturates by fusion of a triazole ring to the 5,6-positions of barbituric acid followed by cleavage and thermal elimination of nitrogen, whereas aza-Wittig reaction gave phosphoranylidene barbituric acid salts.

Original languageEnglish (US)
Pages (from-to)1019-1022
Number of pages4
JournalCentral European Journal of Chemistry
Volume11
Issue number6
DOIs
StatePublished - Dec 1 2013

Keywords

  • Aza-Wittig reaction
  • Azide
  • Barbiturate
  • Pyrimidine

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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  • Cite this

    Lebedyeva, I. O., Sileno, S. M., Patel, K., Ghiviriga, I., Steel, P. J., & Katritzky, A. R. (2013). Reaction of barbituric acid with organic azides and phosphonium ylides. Central European Journal of Chemistry, 11(6), 1019-1022. https://doi.org/10.2478/s11532-013-0233-4