Reconsidering the difference between mixed gonadal dysgenesis and true hermaphroditism

J. W. Akin, S. P.T. Tho, Paul G McDonough

Research output: Contribution to journalArticle

2 Scopus citations


Study Objective. To consider the similarities and differences between mixed gonadal dysgenesis and true hermaphrotidism. Design: A single patient meeting the strict definitional criteria of both mixed gonadal dysgenesis and true hermaphroditism is presented. Setting: Reproductive Endocrinology Division, Medical College of Georgia. Participant: 45,X/46,XY child with sexual ambiguity. Interventions: Surgical assignment of female gender and removal of a gonadoblastoma. Conclusions. The present patient demonstrates the confusion that may arise in the strict definitional categorization of intersex disorders. Until better diagnostic capabilities are developed, we propose excluding altogether individuals with a 45,X cell line by definition from the diagnosis of true hermaphroditism.

Original languageEnglish (US)
Pages (from-to)102-104
Number of pages3
JournalAdolescent and Pediatric Gynecology
Issue number2
Publication statusPublished - Jan 1 1993



  • Gonadal dysgenesis
  • True hermaphrodite

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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