Rectal Adenocarcinoma with Germ-Cell Differentiation: Report of a Case

Teresa A. Coleman, Charles D. Redger, Randy L. Hamill, Paul M Dainer

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A 26-year-old male presented with a colorectal adenocarcinoma with germ-cell differentiation and an isolated elevation of serum alpha-fetoprotein. He was treated with platinum/etoposide/bleomycin chemotherapy with a decrease in serum alpha-fetoprotein and in the size of the primary tumor. An ongoing tumor-marker response occurred when the patient was switched to concurrent 5-fluorouracil chemotherapy and radiation therapy. The patient underwent a palliative diversion of his rectal cancer 10 months after diagnosis, developed liver metastasis at 12 months, and died 20 months after diagnosis.

Original languageEnglish (US)
Pages (from-to)1702-1705
Number of pages4
JournalDiseases of the Colon and Rectum
Volume46
Issue number12
DOIs
StatePublished - Dec 2003
Externally publishedYes

Keywords

  • Alpha-fetoprotein
  • Colorectal carcinoma
  • Germ-cell differentiation
  • Platinum/etoposide/ bleomycin chemotherapy

ASJC Scopus subject areas

  • Gastroenterology

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