Abstract
A 26-year-old male presented with a colorectal adenocarcinoma with germ-cell differentiation and an isolated elevation of serum alpha-fetoprotein. He was treated with platinum/etoposide/bleomycin chemotherapy with a decrease in serum alpha-fetoprotein and in the size of the primary tumor. An ongoing tumor-marker response occurred when the patient was switched to concurrent 5-fluorouracil chemotherapy and radiation therapy. The patient underwent a palliative diversion of his rectal cancer 10 months after diagnosis, developed liver metastasis at 12 months, and died 20 months after diagnosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1702-1705 |
| Number of pages | 4 |
| Journal | Diseases of the Colon and Rectum |
| Volume | 46 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 2003 |
| Externally published | Yes |
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Keywords
- Alpha-fetoprotein
- Colorectal carcinoma
- Germ-cell differentiation
- Platinum/etoposide/ bleomycin chemotherapy
ASJC Scopus subject areas
- Gastroenterology
Cite this
Rectal Adenocarcinoma with Germ-Cell Differentiation : Report of a Case. / Coleman, Teresa A.; Redger, Charles D.; Hamill, Randy L.; Dainer, Paul M.
In: Diseases of the Colon and Rectum, Vol. 46, No. 12, 12.2003, p. 1702-1705.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rectal Adenocarcinoma with Germ-Cell Differentiation
T2 - Report of a Case
AU - Coleman, Teresa A.
AU - Redger, Charles D.
AU - Hamill, Randy L.
AU - Dainer, Paul M
PY - 2003/12
Y1 - 2003/12
N2 - A 26-year-old male presented with a colorectal adenocarcinoma with germ-cell differentiation and an isolated elevation of serum alpha-fetoprotein. He was treated with platinum/etoposide/bleomycin chemotherapy with a decrease in serum alpha-fetoprotein and in the size of the primary tumor. An ongoing tumor-marker response occurred when the patient was switched to concurrent 5-fluorouracil chemotherapy and radiation therapy. The patient underwent a palliative diversion of his rectal cancer 10 months after diagnosis, developed liver metastasis at 12 months, and died 20 months after diagnosis.
AB - A 26-year-old male presented with a colorectal adenocarcinoma with germ-cell differentiation and an isolated elevation of serum alpha-fetoprotein. He was treated with platinum/etoposide/bleomycin chemotherapy with a decrease in serum alpha-fetoprotein and in the size of the primary tumor. An ongoing tumor-marker response occurred when the patient was switched to concurrent 5-fluorouracil chemotherapy and radiation therapy. The patient underwent a palliative diversion of his rectal cancer 10 months after diagnosis, developed liver metastasis at 12 months, and died 20 months after diagnosis.
KW - Alpha-fetoprotein
KW - Colorectal carcinoma
KW - Germ-cell differentiation
KW - Platinum/etoposide/ bleomycin chemotherapy
UR - http://www.scopus.com/inward/record.url?scp=0346780670&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0346780670&partnerID=8YFLogxK
U2 - 10.1007/BF02660779
DO - 10.1007/BF02660779
M3 - Article
C2 - 14668599
AN - SCOPUS:0346780670
VL - 46
SP - 1702
EP - 1705
JO - Diseases of the Colon and Rectum
JF - Diseases of the Colon and Rectum
SN - 0012-3706
IS - 12
ER -