Reference range for tissue oxygen saturation in pregnancy using near-infrared spectroscopy

Robert D. Stager, Mona A. Fakih, Ruth Churley-Strom, Bonita Singal, Mary Anne Purtill

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To estimate the reference range of tissue oxygen saturation (StO2) values in pregnancy. Near-infrared spectroscopy-derived StO2 is a noninvasive continuous measure used to predict hypoperfusion. Normal StO2 values have not been established in pregnant women.

STUDY DESIGN: We enrolled 154 healthy pregnant women from an obstetric and gynecology resident clinic. Three sequential measurements were taken after securing the StO2 probe to the thenar eminence of one hand. One-way ANOVA was used to test for differences between trimesters and non-parametric methods to establish a reference range with 95% CI on the limits.

RESULTS: The reference interval for the entire cohort of pregnant women is 73% (95% CI 72-75) to 92% (95% CI 89-93), similar to the normal range in the general population. We found no statistically significant difference in StO2 measurements between trimesters. Due to inadequate sample sizes we could not estimate a valid reference range for each trimester.

CONCLUSION: We estimated a reference range for StO2 values in normal pregnant women. This information may contribute to the study of StO2 monitoring to predict impending shock in the obstetric patient.

Original languageEnglish (US)
Pages (from-to)149-154
Number of pages6
JournalJournal of Reproductive Medicine
Volume60
Issue number3-4
StatePublished - Mar 1 2015
Externally publishedYes

Fingerprint

Near-Infrared Spectroscopy
Reference Values
Oxygen
Pregnancy
Pregnant Women
Obstetrics
Gynecology
Sample Size
Shock
Analysis of Variance
Hand
Population

Keywords

  • Hypoperfusion
  • Monitoring
  • Oxygen
  • Pregnancy
  • Tissue hypoperfusion
  • Tissue oxygen saturation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Stager, R. D., Fakih, M. A., Churley-Strom, R., Singal, B., & Purtill, M. A. (2015). Reference range for tissue oxygen saturation in pregnancy using near-infrared spectroscopy. Journal of Reproductive Medicine, 60(3-4), 149-154.

Reference range for tissue oxygen saturation in pregnancy using near-infrared spectroscopy. / Stager, Robert D.; Fakih, Mona A.; Churley-Strom, Ruth; Singal, Bonita; Purtill, Mary Anne.

In: Journal of Reproductive Medicine, Vol. 60, No. 3-4, 01.03.2015, p. 149-154.

Research output: Contribution to journalArticle

Stager, RD, Fakih, MA, Churley-Strom, R, Singal, B & Purtill, MA 2015, 'Reference range for tissue oxygen saturation in pregnancy using near-infrared spectroscopy', Journal of Reproductive Medicine, vol. 60, no. 3-4, pp. 149-154.
Stager RD, Fakih MA, Churley-Strom R, Singal B, Purtill MA. Reference range for tissue oxygen saturation in pregnancy using near-infrared spectroscopy. Journal of Reproductive Medicine. 2015 Mar 1;60(3-4):149-154.
Stager, Robert D. ; Fakih, Mona A. ; Churley-Strom, Ruth ; Singal, Bonita ; Purtill, Mary Anne. / Reference range for tissue oxygen saturation in pregnancy using near-infrared spectroscopy. In: Journal of Reproductive Medicine. 2015 ; Vol. 60, No. 3-4. pp. 149-154.
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