Report From the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective Nodal Irradiation in Lung Cancer

Small-Cell Lung Cancer (SCLC)

Gregory M.M. Videtic, José S.A. Belderbos, Feng Ming Kong, Lucyna Kepka, Mary K. Martel, Branislav Jeremic

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Thoracic radiotherapy (RT) is an integral part of the management of small-cell lung cancer (SCLC) because its administration provides a survival benefit in patients with limited-stage disease. However, there are many areas of controversy with respect to the delivery of curative RT, and these include definition of the target to be irradiated. A current area of concern is defining what the RT portal must encompass with respect to the mediastinal lymph nodes; that is, whether one should electively treat all mediastinal nodes, or selectively include those with some clinical risk for harboring disease, or perhaps omit elective nodal irradiation altogether. The purpose of the present report is therefore to address the concepts underlying elective or selective nodal irradiation as it applies to SCLC, looking at clinical, imaging, and RT reports to help define the parameters appropriate to treating individual patients.

Original languageEnglish (US)
Pages (from-to)327-334
Number of pages8
JournalInternational Journal of Radiation Oncology Biology Physics
Volume72
Issue number2
DOIs
StatePublished - Oct 1 2008

Fingerprint

Nuclear Energy
Small Cell Lung Carcinoma
Consultants
nuclear energy
lungs
radiation therapy
Lung Neoplasms
Radiotherapy
cancer
irradiation
lymphatic system
delivery
Thorax
Lymph Nodes
Survival

Keywords

  • Elective nodal irradiation
  • Radiotherapy planning
  • Small-cell lung cancer

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

Cite this

Report From the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective Nodal Irradiation in Lung Cancer : Small-Cell Lung Cancer (SCLC). / Videtic, Gregory M.M.; Belderbos, José S.A.; Kong, Feng Ming; Kepka, Lucyna; Martel, Mary K.; Jeremic, Branislav.

In: International Journal of Radiation Oncology Biology Physics, Vol. 72, No. 2, 01.10.2008, p. 327-334.

Research output: Contribution to journalArticle

Videtic, Gregory M.M. ; Belderbos, José S.A. ; Kong, Feng Ming ; Kepka, Lucyna ; Martel, Mary K. ; Jeremic, Branislav. / Report From the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective Nodal Irradiation in Lung Cancer : Small-Cell Lung Cancer (SCLC). In: International Journal of Radiation Oncology Biology Physics. 2008 ; Vol. 72, No. 2. pp. 327-334.
@article{abdb5dbcadcb41bb961a9acc2355ff16,
title = "Report From the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective Nodal Irradiation in Lung Cancer: Small-Cell Lung Cancer (SCLC)",
abstract = "Thoracic radiotherapy (RT) is an integral part of the management of small-cell lung cancer (SCLC) because its administration provides a survival benefit in patients with limited-stage disease. However, there are many areas of controversy with respect to the delivery of curative RT, and these include definition of the target to be irradiated. A current area of concern is defining what the RT portal must encompass with respect to the mediastinal lymph nodes; that is, whether one should electively treat all mediastinal nodes, or selectively include those with some clinical risk for harboring disease, or perhaps omit elective nodal irradiation altogether. The purpose of the present report is therefore to address the concepts underlying elective or selective nodal irradiation as it applies to SCLC, looking at clinical, imaging, and RT reports to help define the parameters appropriate to treating individual patients.",
keywords = "Elective nodal irradiation, Radiotherapy planning, Small-cell lung cancer",
author = "Videtic, {Gregory M.M.} and Belderbos, {Jos{\'e} S.A.} and Kong, {Feng Ming} and Lucyna Kepka and Martel, {Mary K.} and Branislav Jeremic",
year = "2008",
month = "10",
day = "1",
doi = "10.1016/j.ijrobp.2008.03.075",
language = "English (US)",
volume = "72",
pages = "327--334",
journal = "International Journal of Radiation Oncology Biology Physics",
issn = "0360-3016",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Report From the International Atomic Energy Agency (IAEA) Consultants' Meeting on Elective Nodal Irradiation in Lung Cancer

T2 - Small-Cell Lung Cancer (SCLC)

AU - Videtic, Gregory M.M.

AU - Belderbos, José S.A.

AU - Kong, Feng Ming

AU - Kepka, Lucyna

AU - Martel, Mary K.

AU - Jeremic, Branislav

PY - 2008/10/1

Y1 - 2008/10/1

N2 - Thoracic radiotherapy (RT) is an integral part of the management of small-cell lung cancer (SCLC) because its administration provides a survival benefit in patients with limited-stage disease. However, there are many areas of controversy with respect to the delivery of curative RT, and these include definition of the target to be irradiated. A current area of concern is defining what the RT portal must encompass with respect to the mediastinal lymph nodes; that is, whether one should electively treat all mediastinal nodes, or selectively include those with some clinical risk for harboring disease, or perhaps omit elective nodal irradiation altogether. The purpose of the present report is therefore to address the concepts underlying elective or selective nodal irradiation as it applies to SCLC, looking at clinical, imaging, and RT reports to help define the parameters appropriate to treating individual patients.

AB - Thoracic radiotherapy (RT) is an integral part of the management of small-cell lung cancer (SCLC) because its administration provides a survival benefit in patients with limited-stage disease. However, there are many areas of controversy with respect to the delivery of curative RT, and these include definition of the target to be irradiated. A current area of concern is defining what the RT portal must encompass with respect to the mediastinal lymph nodes; that is, whether one should electively treat all mediastinal nodes, or selectively include those with some clinical risk for harboring disease, or perhaps omit elective nodal irradiation altogether. The purpose of the present report is therefore to address the concepts underlying elective or selective nodal irradiation as it applies to SCLC, looking at clinical, imaging, and RT reports to help define the parameters appropriate to treating individual patients.

KW - Elective nodal irradiation

KW - Radiotherapy planning

KW - Small-cell lung cancer

UR - http://www.scopus.com/inward/record.url?scp=51449108879&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51449108879&partnerID=8YFLogxK

U2 - 10.1016/j.ijrobp.2008.03.075

DO - 10.1016/j.ijrobp.2008.03.075

M3 - Article

VL - 72

SP - 327

EP - 334

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

SN - 0360-3016

IS - 2

ER -