Reproductive hormone exposure timing and ischemic heart disease: Complicated answers to a simple question

C. Noel Bairey Merz, Chrisandra Shufelt, B. Delia Johnson, Ricardo Azziz, Glenn D. Braunstein

Research output: Contribution to journalEditorial

6 Scopus citations

Abstract

The current literature, combined with improved methodology in the WISE study, suggests that there is a beneficial relation between HT use and IHD in peri- and early postmenopausal women. Our results are also consistent with recent clinical trials that have failed to show benefit of HT initiation in older postmenopausal women, either for angiographic coronary disease or cardiac events. Overall, our data suggest that the anti-atherosclerotic effect of HT, if present, may be age-dependent and primarily evident in relatively younger peri- and early postmenopausal women.

Original languageEnglish (US)
Pages (from-to)297-298
Number of pages2
JournalMaturitas
Volume65
Issue number4
DOIs
Publication statusPublished - Apr 1 2010

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Keywords

  • Hormone
  • Ischemic heart disease
  • Reproductive

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Obstetrics and Gynecology

Cite this

Bairey Merz, C. N., Shufelt, C., Johnson, B. D., Azziz, R., & Braunstein, G. D. (2010). Reproductive hormone exposure timing and ischemic heart disease: Complicated answers to a simple question. Maturitas, 65(4), 297-298. https://doi.org/10.1016/j.maturitas.2010.01.003