Reversal of compromised bonding to oxidized etched dentin

S. C.N. Lai, Y. F. Mak, G. S.P. Cheung, R. Osorio, M. Toledano, R. M. Carvalho, F. R. Tay, D. H. Pashley

Research output: Contribution to journalArticle

190 Citations (Scopus)

Abstract

The mechanism responsible for hydrogenperoxide- or sodium-hypochlorite-induced reductions in dentin bond strength is unknown. This in vitro study tested the hypothesis that these oxidizing agents were responsible by attempting to reverse the effect with sodium ascorbate, a reducing agent. Human dentin was treated with these oxidants before or after being acid-etched and with or without post-treatment with sodium ascorbate. They were bonded with either Single Bond or Excite. Hydrogen peroxide reduced the bond strengths of both adhesives, while sodium hypochlorite produced reduction in adhesion of only Single Bond (p < 0.05). Following treatment with sodium ascorbate, reductions in bond strength were reversed. Transmission and scanning electron microscopy showed partial removal of the demineralized collagen matrix only by sodium hypochlorite. The observed compromised bond strengths cannot be attributed to incomplete deproteinization and may be related to changes in the redox potential of the bonding substrates.

Original languageEnglish (US)
Pages (from-to)1919-1924
Number of pages6
JournalJournal of Dental Research
Volume80
Issue number10
DOIs
StatePublished - Jan 1 2001

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Sodium Hypochlorite
Dentin
Ascorbic Acid
Oxidants
Scanning Transmission Electron Microscopy
Reducing Agents
Adhesives
Hydrogen Peroxide
Oxidation-Reduction
Collagen
Acids
single bond

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Lai, S. C. N., Mak, Y. F., Cheung, G. S. P., Osorio, R., Toledano, M., Carvalho, R. M., ... Pashley, D. H. (2001). Reversal of compromised bonding to oxidized etched dentin. Journal of Dental Research, 80(10), 1919-1924. https://doi.org/10.1177/00220345010800101101

Reversal of compromised bonding to oxidized etched dentin. / Lai, S. C.N.; Mak, Y. F.; Cheung, G. S.P.; Osorio, R.; Toledano, M.; Carvalho, R. M.; Tay, F. R.; Pashley, D. H.

In: Journal of Dental Research, Vol. 80, No. 10, 01.01.2001, p. 1919-1924.

Research output: Contribution to journalArticle

Lai, SCN, Mak, YF, Cheung, GSP, Osorio, R, Toledano, M, Carvalho, RM, Tay, FR & Pashley, DH 2001, 'Reversal of compromised bonding to oxidized etched dentin', Journal of Dental Research, vol. 80, no. 10, pp. 1919-1924. https://doi.org/10.1177/00220345010800101101
Lai SCN, Mak YF, Cheung GSP, Osorio R, Toledano M, Carvalho RM et al. Reversal of compromised bonding to oxidized etched dentin. Journal of Dental Research. 2001 Jan 1;80(10):1919-1924. https://doi.org/10.1177/00220345010800101101
Lai, S. C.N. ; Mak, Y. F. ; Cheung, G. S.P. ; Osorio, R. ; Toledano, M. ; Carvalho, R. M. ; Tay, F. R. ; Pashley, D. H. / Reversal of compromised bonding to oxidized etched dentin. In: Journal of Dental Research. 2001 ; Vol. 80, No. 10. pp. 1919-1924.
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