Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal

K. J. Meador, D. W. Loring, G. P. Lee, B. S. Brooks, E. E. Thompson, W. O. Thompson, K. M. Heilman

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Although several components of neglect syndrome have been reported to occur more frequently following right cerebral lesions, a right cerebral predominance for directed tactile attention has not been demonstrated. The intracarotid sodium amytal procedure (ISA, or Wada test) offers the opportunity to investigate differential effects for symmetric acute dysfunction of each cerebral hemisphere in each subject. In the present study, 18 patients undergoing preoperative evaluation for epilepsy surgery were trained in a nonverbal task of tactile attention. Left/right mean ISA dosages and left/right tactile test times postinjection were matched. Results revealed more correct responses following left ISA, and greater tactile inattention with more extinction-type responses following right ISA. No effect of seizure focus, sex, order of injection, or dosage was present. The finding that tactile inattention occurs more frequently with right cerebral dysfunction is consistent with right cerebral dominance for scanning attentional mechanisms directed at the external milieu.

Original languageEnglish (US)
Pages (from-to)1763-1766
Number of pages4
JournalNeurology
Volume38
Issue number11
StatePublished - Jan 1 1988

Fingerprint

Amobarbital
Touch
Cerebral Dominance
Cerebrum
Epilepsy
Seizures
Injections

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Meador, K. J., Loring, D. W., Lee, G. P., Brooks, B. S., Thompson, E. E., Thompson, W. O., & Heilman, K. M. (1988). Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal. Neurology, 38(11), 1763-1766.

Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal. / Meador, K. J.; Loring, D. W.; Lee, G. P.; Brooks, B. S.; Thompson, E. E.; Thompson, W. O.; Heilman, K. M.

In: Neurology, Vol. 38, No. 11, 01.01.1988, p. 1763-1766.

Research output: Contribution to journalArticle

Meador, KJ, Loring, DW, Lee, GP, Brooks, BS, Thompson, EE, Thompson, WO & Heilman, KM 1988, 'Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal', Neurology, vol. 38, no. 11, pp. 1763-1766.
Meador KJ, Loring DW, Lee GP, Brooks BS, Thompson EE, Thompson WO et al. Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal. Neurology. 1988 Jan 1;38(11):1763-1766.
Meador, K. J. ; Loring, D. W. ; Lee, G. P. ; Brooks, B. S. ; Thompson, E. E. ; Thompson, W. O. ; Heilman, K. M. / Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal. In: Neurology. 1988 ; Vol. 38, No. 11. pp. 1763-1766.
@article{2afeb1e3ae3f43a48b1c0bd1058fe717,
title = "Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal",
abstract = "Although several components of neglect syndrome have been reported to occur more frequently following right cerebral lesions, a right cerebral predominance for directed tactile attention has not been demonstrated. The intracarotid sodium amytal procedure (ISA, or Wada test) offers the opportunity to investigate differential effects for symmetric acute dysfunction of each cerebral hemisphere in each subject. In the present study, 18 patients undergoing preoperative evaluation for epilepsy surgery were trained in a nonverbal task of tactile attention. Left/right mean ISA dosages and left/right tactile test times postinjection were matched. Results revealed more correct responses following left ISA, and greater tactile inattention with more extinction-type responses following right ISA. No effect of seizure focus, sex, order of injection, or dosage was present. The finding that tactile inattention occurs more frequently with right cerebral dysfunction is consistent with right cerebral dominance for scanning attentional mechanisms directed at the external milieu.",
author = "Meador, {K. J.} and Loring, {D. W.} and Lee, {G. P.} and Brooks, {B. S.} and Thompson, {E. E.} and Thompson, {W. O.} and Heilman, {K. M.}",
year = "1988",
month = "1",
day = "1",
language = "English (US)",
volume = "38",
pages = "1763--1766",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "11",

}

TY - JOUR

T1 - Right cerebral specialization for tactile attention as evidenced by intracarotid sodium amytal

AU - Meador, K. J.

AU - Loring, D. W.

AU - Lee, G. P.

AU - Brooks, B. S.

AU - Thompson, E. E.

AU - Thompson, W. O.

AU - Heilman, K. M.

PY - 1988/1/1

Y1 - 1988/1/1

N2 - Although several components of neglect syndrome have been reported to occur more frequently following right cerebral lesions, a right cerebral predominance for directed tactile attention has not been demonstrated. The intracarotid sodium amytal procedure (ISA, or Wada test) offers the opportunity to investigate differential effects for symmetric acute dysfunction of each cerebral hemisphere in each subject. In the present study, 18 patients undergoing preoperative evaluation for epilepsy surgery were trained in a nonverbal task of tactile attention. Left/right mean ISA dosages and left/right tactile test times postinjection were matched. Results revealed more correct responses following left ISA, and greater tactile inattention with more extinction-type responses following right ISA. No effect of seizure focus, sex, order of injection, or dosage was present. The finding that tactile inattention occurs more frequently with right cerebral dysfunction is consistent with right cerebral dominance for scanning attentional mechanisms directed at the external milieu.

AB - Although several components of neglect syndrome have been reported to occur more frequently following right cerebral lesions, a right cerebral predominance for directed tactile attention has not been demonstrated. The intracarotid sodium amytal procedure (ISA, or Wada test) offers the opportunity to investigate differential effects for symmetric acute dysfunction of each cerebral hemisphere in each subject. In the present study, 18 patients undergoing preoperative evaluation for epilepsy surgery were trained in a nonverbal task of tactile attention. Left/right mean ISA dosages and left/right tactile test times postinjection were matched. Results revealed more correct responses following left ISA, and greater tactile inattention with more extinction-type responses following right ISA. No effect of seizure focus, sex, order of injection, or dosage was present. The finding that tactile inattention occurs more frequently with right cerebral dysfunction is consistent with right cerebral dominance for scanning attentional mechanisms directed at the external milieu.

UR - http://www.scopus.com/inward/record.url?scp=0023775762&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023775762&partnerID=8YFLogxK

M3 - Article

C2 - 3185912

AN - SCOPUS:0023775762

VL - 38

SP - 1763

EP - 1766

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 11

ER -