Risk factors for cervical cancer among HPV positive women in Mexico

Yvonne N. Flores, David M. Bishai, Keerti V. Shah, Eduardo Lazcano-Ponce, Attila Lörincz, Mauricio Hernández, Daron Gale Ferris, Jorge Salmerón

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective. To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico. Material and Methods. A case-control study design was used. A total of 94 cases and 501 controls who met the study inclusion criteria were selected from the 7 732 women who participated in the Morelos HPV Study from May 1999 to June 2000. Risk factor information was obtained from interviews and from HPV viral load results. Odds ratios and 95 percent confidence intervals were estimated using unconditional multivariate regression. Results. Increasing age, high viral load, a young age at first sexual intercourse, and a low socio-economic status are associated with an increased risk of disease among HPV-positive women. Conclusions. These results could have important implications for future screening activities in Mexico and other low resource countries.

Original languageEnglish (US)
Pages (from-to)49-58
Number of pages10
JournalSalud Publica de Mexico
Volume50
Issue number1
DOIs
StatePublished - Jan 1 2008

Fingerprint

Mexico
Uterine Cervical Neoplasms
Coitus
Viral Load
Cervical Intraepithelial Neoplasia
Case-Control Studies
Odds Ratio
Economics
Confidence Intervals
Interviews
Neoplasms

Keywords

  • Cervical cancer
  • HPV
  • Mexico
  • Risk factors
  • Screening

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Flores, Y. N., Bishai, D. M., Shah, K. V., Lazcano-Ponce, E., Lörincz, A., Hernández, M., ... Salmerón, J. (2008). Risk factors for cervical cancer among HPV positive women in Mexico. Salud Publica de Mexico, 50(1), 49-58. https://doi.org/10.1590/S0036-36342008000100011

Risk factors for cervical cancer among HPV positive women in Mexico. / Flores, Yvonne N.; Bishai, David M.; Shah, Keerti V.; Lazcano-Ponce, Eduardo; Lörincz, Attila; Hernández, Mauricio; Ferris, Daron Gale; Salmerón, Jorge.

In: Salud Publica de Mexico, Vol. 50, No. 1, 01.01.2008, p. 49-58.

Research output: Contribution to journalArticle

Flores, YN, Bishai, DM, Shah, KV, Lazcano-Ponce, E, Lörincz, A, Hernández, M, Ferris, DG & Salmerón, J 2008, 'Risk factors for cervical cancer among HPV positive women in Mexico', Salud Publica de Mexico, vol. 50, no. 1, pp. 49-58. https://doi.org/10.1590/S0036-36342008000100011
Flores YN, Bishai DM, Shah KV, Lazcano-Ponce E, Lörincz A, Hernández M et al. Risk factors for cervical cancer among HPV positive women in Mexico. Salud Publica de Mexico. 2008 Jan 1;50(1):49-58. https://doi.org/10.1590/S0036-36342008000100011
Flores, Yvonne N. ; Bishai, David M. ; Shah, Keerti V. ; Lazcano-Ponce, Eduardo ; Lörincz, Attila ; Hernández, Mauricio ; Ferris, Daron Gale ; Salmerón, Jorge. / Risk factors for cervical cancer among HPV positive women in Mexico. In: Salud Publica de Mexico. 2008 ; Vol. 50, No. 1. pp. 49-58.
@article{43dcb46e5373445dbb1d9e16cf48b437,
title = "Risk factors for cervical cancer among HPV positive women in Mexico",
abstract = "Objective. To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico. Material and Methods. A case-control study design was used. A total of 94 cases and 501 controls who met the study inclusion criteria were selected from the 7 732 women who participated in the Morelos HPV Study from May 1999 to June 2000. Risk factor information was obtained from interviews and from HPV viral load results. Odds ratios and 95 percent confidence intervals were estimated using unconditional multivariate regression. Results. Increasing age, high viral load, a young age at first sexual intercourse, and a low socio-economic status are associated with an increased risk of disease among HPV-positive women. Conclusions. These results could have important implications for future screening activities in Mexico and other low resource countries.",
keywords = "Cervical cancer, HPV, Mexico, Risk factors, Screening",
author = "Flores, {Yvonne N.} and Bishai, {David M.} and Shah, {Keerti V.} and Eduardo Lazcano-Ponce and Attila L{\"o}rincz and Mauricio Hern{\'a}ndez and Ferris, {Daron Gale} and Jorge Salmer{\'o}n",
year = "2008",
month = "1",
day = "1",
doi = "10.1590/S0036-36342008000100011",
language = "English (US)",
volume = "50",
pages = "49--58",
journal = "Salud Publica de Mexico",
issn = "0036-3634",
publisher = "Instituto Nacional de Salud Publica",
number = "1",

}

TY - JOUR

T1 - Risk factors for cervical cancer among HPV positive women in Mexico

AU - Flores, Yvonne N.

AU - Bishai, David M.

AU - Shah, Keerti V.

AU - Lazcano-Ponce, Eduardo

AU - Lörincz, Attila

AU - Hernández, Mauricio

AU - Ferris, Daron Gale

AU - Salmerón, Jorge

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Objective. To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico. Material and Methods. A case-control study design was used. A total of 94 cases and 501 controls who met the study inclusion criteria were selected from the 7 732 women who participated in the Morelos HPV Study from May 1999 to June 2000. Risk factor information was obtained from interviews and from HPV viral load results. Odds ratios and 95 percent confidence intervals were estimated using unconditional multivariate regression. Results. Increasing age, high viral load, a young age at first sexual intercourse, and a low socio-economic status are associated with an increased risk of disease among HPV-positive women. Conclusions. These results could have important implications for future screening activities in Mexico and other low resource countries.

AB - Objective. To identify factors that are associated with an increased risk of developing high-grade cervical intraepithelial neoplasia (CIN) or cancer among human papillomavirus (HPV)-positive women in Mexico. Material and Methods. A case-control study design was used. A total of 94 cases and 501 controls who met the study inclusion criteria were selected from the 7 732 women who participated in the Morelos HPV Study from May 1999 to June 2000. Risk factor information was obtained from interviews and from HPV viral load results. Odds ratios and 95 percent confidence intervals were estimated using unconditional multivariate regression. Results. Increasing age, high viral load, a young age at first sexual intercourse, and a low socio-economic status are associated with an increased risk of disease among HPV-positive women. Conclusions. These results could have important implications for future screening activities in Mexico and other low resource countries.

KW - Cervical cancer

KW - HPV

KW - Mexico

KW - Risk factors

KW - Screening

UR - http://www.scopus.com/inward/record.url?scp=42349088283&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42349088283&partnerID=8YFLogxK

U2 - 10.1590/S0036-36342008000100011

DO - 10.1590/S0036-36342008000100011

M3 - Article

C2 - 18297182

AN - SCOPUS:42349088283

VL - 50

SP - 49

EP - 58

JO - Salud Publica de Mexico

JF - Salud Publica de Mexico

SN - 0036-3634

IS - 1

ER -