TY - JOUR
T1 - Risk Factors for Dental Implant Failure in Private Practice
T2 - A Multicenter Survival Analysis
AU - Schoenbaum, Todd R.
AU - Moy, Peter K.
AU - Aghaloo, Tara
AU - Elashoff, David
N1 - Funding Information:
The authors would like to thank the faculty of the UCLA Department of Computational Medicine for their guidance in study design and biostatistical analysis, Dr Reuben Kim and the section of restorative dentistry at UCLA for financial support, Sitaram Vangala, MS, for performing the robust standard errors tests, Drs Alexandre-Amir Aalam/ Alina Krivitsky, Bach Le, Christopher Barrett/Justin Moody, Hooman Zarenkelk, HZ, Michael Block, MH, and SK for access to records for data collection, and CTSI Grant UL1TR001881 for use of data collection in REDCAP. All authors gave their final approval and agree to be accountable for all aspects of the work. The authors report no conflict of interest.
Publisher Copyright:
©2021 by Quintessence Publishing Co Inc.
PY - 2021
Y1 - 2021
N2 - Purpose: The objective of this study was to quantify the probability of implant failure over time from intrinsic patient factors using a population of patients from multiple private practices.Materials and Methods: The records for this retrospective, multicenter cohort study were randomly selected from eight private practices. The primary outcome variable was time to event (implant failure or last known follow-up). The included independent variables were age, sex, diabetes status, smoking status, and arch location. Analyses were performed with Cox proportional hazards on three models: univariate, full multivariate, and systemic factor multivariate. The probability of implant survival at 1, 5, and 10 years was calculated using univariate time-to-event modeling on log-normal distribution with 95% CIs and Cox proportional hazard tests for significance. The Kaplan-Meier survival curve was calculated for patients < 71 years of age. Results: Eight hundred thirty-five implant-level records from 378 patients were collected for analyses. The mean patient age was 60 years, and 48% were men, 15% reported a history of smoking, and 16% reported having diabetes. The follow-up time was as long as 17 years, with a mean of 23.1 months, and a median of 7 months. The hazard ratio (HR) for implant failure due to sex (HR = 1.18; 95% CI: 0.52 to 2.66), smoking (HR = 1.30; 95% CI: 0.49 to 3.46), diabetes (HR = 1.17; 95% CI: 0.35 to 3.86), and arch location (HR = 2.13 to 3.39) failed to reach the threshold within any Cox proportional hazards model (P >.05). Conclusion: The implant survival probability for patients ≤ 70 years of age is 86.4% at 10 years in the course of routine private practice by experienced providers. Cautious interpretation of these results is critical, as the effects of known systemic risk factors are likely tempered by effective modifications in clinical decisions and protocols with short- and long-term follow-up maintenance. Int J Oral Maxillofac Implants 2021;36:388–394. doi: 10.11607/jomi.8983
AB - Purpose: The objective of this study was to quantify the probability of implant failure over time from intrinsic patient factors using a population of patients from multiple private practices.Materials and Methods: The records for this retrospective, multicenter cohort study were randomly selected from eight private practices. The primary outcome variable was time to event (implant failure or last known follow-up). The included independent variables were age, sex, diabetes status, smoking status, and arch location. Analyses were performed with Cox proportional hazards on three models: univariate, full multivariate, and systemic factor multivariate. The probability of implant survival at 1, 5, and 10 years was calculated using univariate time-to-event modeling on log-normal distribution with 95% CIs and Cox proportional hazard tests for significance. The Kaplan-Meier survival curve was calculated for patients < 71 years of age. Results: Eight hundred thirty-five implant-level records from 378 patients were collected for analyses. The mean patient age was 60 years, and 48% were men, 15% reported a history of smoking, and 16% reported having diabetes. The follow-up time was as long as 17 years, with a mean of 23.1 months, and a median of 7 months. The hazard ratio (HR) for implant failure due to sex (HR = 1.18; 95% CI: 0.52 to 2.66), smoking (HR = 1.30; 95% CI: 0.49 to 3.46), diabetes (HR = 1.17; 95% CI: 0.35 to 3.86), and arch location (HR = 2.13 to 3.39) failed to reach the threshold within any Cox proportional hazards model (P >.05). Conclusion: The implant survival probability for patients ≤ 70 years of age is 86.4% at 10 years in the course of routine private practice by experienced providers. Cautious interpretation of these results is critical, as the effects of known systemic risk factors are likely tempered by effective modifications in clinical decisions and protocols with short- and long-term follow-up maintenance. Int J Oral Maxillofac Implants 2021;36:388–394. doi: 10.11607/jomi.8983
KW - dentistry
KW - implants
KW - risk
KW - survival
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U2 - 10.11607/jomi.8983
DO - 10.11607/jomi.8983
M3 - Article
C2 - 33909732
AN - SCOPUS:85105049960
SN - 0882-2786
VL - 36
SP - 388
EP - 394
JO - The International journal of oral & maxillofacial implants
JF - The International journal of oral & maxillofacial implants
IS - 2
ER -