Role of adenosine in diabetic retinopathy

Gregory I Liou, Saif Ahmad, Mohammad Naime, Nadeem Fatteh, Ahmed Salah Ibrahim

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

In diabetic retinopathy (DR), abnormalities in vascular and neuronal function are closely related to the local production of inflammatory mediators whose potential source is microglia. Adenosine and its receptors have been shown to possess anti-inflammatory properties that have only recently been studied in DR. Here, we review recent studies that determined the roles of adenosine and its associated proteins, including equilibrative nucleoside transporters, adenosine receptors, and underlying signaling pathways in retinal complications associated with diabetes.

Original languageEnglish (US)
Pages (from-to)19-24
Number of pages6
JournalJournal of Ocular Biology, Diseases, and Informatics
Volume4
Issue number1-2
DOIs
StatePublished - Jun 1 2011

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Purinergic P1 Receptors
Diabetic Retinopathy
Adenosine
Nucleoside Transport Proteins
Microglia
Blood Vessels
Anti-Inflammatory Agents
Proteins

Keywords

  • Adenosine
  • Adenosine receptors
  • Cannabinoids
  • Diabetic retinopathy
  • Microglia

ASJC Scopus subject areas

  • Ophthalmology
  • Genetics

Cite this

Liou, G. I., Ahmad, S., Naime, M., Fatteh, N., & Ibrahim, A. S. (2011). Role of adenosine in diabetic retinopathy. Journal of Ocular Biology, Diseases, and Informatics, 4(1-2), 19-24. https://doi.org/10.1007/s12177-011-9067-5

Role of adenosine in diabetic retinopathy. / Liou, Gregory I; Ahmad, Saif; Naime, Mohammad; Fatteh, Nadeem; Ibrahim, Ahmed Salah.

In: Journal of Ocular Biology, Diseases, and Informatics, Vol. 4, No. 1-2, 01.06.2011, p. 19-24.

Research output: Contribution to journalReview article

Liou, GI, Ahmad, S, Naime, M, Fatteh, N & Ibrahim, AS 2011, 'Role of adenosine in diabetic retinopathy', Journal of Ocular Biology, Diseases, and Informatics, vol. 4, no. 1-2, pp. 19-24. https://doi.org/10.1007/s12177-011-9067-5
Liou, Gregory I ; Ahmad, Saif ; Naime, Mohammad ; Fatteh, Nadeem ; Ibrahim, Ahmed Salah. / Role of adenosine in diabetic retinopathy. In: Journal of Ocular Biology, Diseases, and Informatics. 2011 ; Vol. 4, No. 1-2. pp. 19-24.
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