In diabetic retinopathy (DR), abnormalities in vascular and neuronal function are closely related to the local production of inflammatory mediators whose potential source is microglia. Adenosine and its receptors have been shown to possess anti-inflammatory properties that have only recently been studied in DR. Here, we review recent studies that determined the roles of adenosine and its associated proteins, including equilibrative nucleoside transporters, adenosine receptors, and underlying signaling pathways in retinal complications associated with diabetes.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of Ocular Biology, Diseases, and Informatics|
|State||Published - Jun 2011|
- Adenosine receptors
- Diabetic retinopathy
ASJC Scopus subject areas