Role of dentin cross-linking agents in optimizing dentin bond durability

M. Abunawareg, D. A. Abuelenain, D. Elkassas, T. Abu Haimed, A. Al-Dharrab, A. Zidan, A. H. Hassan, David Henry Pashley

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The present work compared the effects of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC-HCl) and ultraviolet (UV)- or blue light-activated riboflavin cross-linking agents on resin–dentin micro-tensile bond strength and nanoleakage in bonds produced using a two-step, etch-and-rinse adhesive after three storage intervals (24 h, 6 months, and 12 months). Forty eight extracted human third molars were used to investigate micro-tensile bond strength and interfacial nanoleakage in resin–dentin bonds created using Adper Single Bond 2, with or without pretreatment of acid-etched dentin surfaces. Either 0.5 M EDC-HCl or 1% riboflavin-5-phosphate activated by blue or UV light were used as cross-linking agents. Samples were evaluated after storage for 24 h, 6 months, or 12 months in distilled water at 37 °C. Statistical analyses revealed that 12 months of storage resulted in significant decreases in the bond strength of the controls (p < 0.003), with significant increases in their silver nanoleakage (p < 0.05), compared with the groups subjected to dentin pretreatment with either EDC-HCl or light-activated 1% riboflavin. Despite the significant drop in bond strength after 6 months’ storage in all experimental groups compared with the 24-h bond strength (p < 0.05), there was a further non-significant drop in bond strength after 12 months in samples treated with EDC-HCl and UV-activated 1% riboflavin (p > 0.05). Dental collagen cross-linking induced by UV- or blue light-activated 1% riboflavin or EDC-HCl enhanced the durability and strength of the resin–dentin bond.

Original languageEnglish (US)
Pages (from-to)83-88
Number of pages6
JournalInternational Journal of Adhesion and Adhesives
Volume78
DOIs
StatePublished - Oct 1 2017

Fingerprint

Carbodiimides
Riboflavin
Durability
Ethyldimethylaminopropyl Carbodiimide
Flavin Mononucleotide
Collagen
Adhesives
Phosphates
Acids
Water
Ultraviolet Rays
Adper single bond 2

Keywords

  • Hybrid layer
  • Micro-tensile
  • Nanoleakage
  • Riboflavin
  • Surface treatment

ASJC Scopus subject areas

  • Biomaterials
  • Chemical Engineering(all)
  • Polymers and Plastics

Cite this

Abunawareg, M., Abuelenain, D. A., Elkassas, D., Haimed, T. A., Al-Dharrab, A., Zidan, A., ... Pashley, D. H. (2017). Role of dentin cross-linking agents in optimizing dentin bond durability. International Journal of Adhesion and Adhesives, 78, 83-88. https://doi.org/10.1016/j.ijadhadh.2017.06.009

Role of dentin cross-linking agents in optimizing dentin bond durability. / Abunawareg, M.; Abuelenain, D. A.; Elkassas, D.; Haimed, T. Abu; Al-Dharrab, A.; Zidan, A.; Hassan, A. H.; Pashley, David Henry.

In: International Journal of Adhesion and Adhesives, Vol. 78, 01.10.2017, p. 83-88.

Research output: Contribution to journalArticle

Abunawareg, M, Abuelenain, DA, Elkassas, D, Haimed, TA, Al-Dharrab, A, Zidan, A, Hassan, AH & Pashley, DH 2017, 'Role of dentin cross-linking agents in optimizing dentin bond durability', International Journal of Adhesion and Adhesives, vol. 78, pp. 83-88. https://doi.org/10.1016/j.ijadhadh.2017.06.009
Abunawareg, M. ; Abuelenain, D. A. ; Elkassas, D. ; Haimed, T. Abu ; Al-Dharrab, A. ; Zidan, A. ; Hassan, A. H. ; Pashley, David Henry. / Role of dentin cross-linking agents in optimizing dentin bond durability. In: International Journal of Adhesion and Adhesives. 2017 ; Vol. 78. pp. 83-88.
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abstract = "The present work compared the effects of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC-HCl) and ultraviolet (UV)- or blue light-activated riboflavin cross-linking agents on resin–dentin micro-tensile bond strength and nanoleakage in bonds produced using a two-step, etch-and-rinse adhesive after three storage intervals (24 h, 6 months, and 12 months). Forty eight extracted human third molars were used to investigate micro-tensile bond strength and interfacial nanoleakage in resin–dentin bonds created using Adper Single Bond 2, with or without pretreatment of acid-etched dentin surfaces. Either 0.5 M EDC-HCl or 1{\%} riboflavin-5-phosphate activated by blue or UV light were used as cross-linking agents. Samples were evaluated after storage for 24 h, 6 months, or 12 months in distilled water at 37 °C. Statistical analyses revealed that 12 months of storage resulted in significant decreases in the bond strength of the controls (p < 0.003), with significant increases in their silver nanoleakage (p < 0.05), compared with the groups subjected to dentin pretreatment with either EDC-HCl or light-activated 1{\%} riboflavin. Despite the significant drop in bond strength after 6 months’ storage in all experimental groups compared with the 24-h bond strength (p < 0.05), there was a further non-significant drop in bond strength after 12 months in samples treated with EDC-HCl and UV-activated 1{\%} riboflavin (p > 0.05). Dental collagen cross-linking induced by UV- or blue light-activated 1{\%} riboflavin or EDC-HCl enhanced the durability and strength of the resin–dentin bond.",
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AU - Abuelenain, D. A.

AU - Elkassas, D.

AU - Haimed, T. Abu

AU - Al-Dharrab, A.

AU - Zidan, A.

AU - Hassan, A. H.

AU - Pashley, David Henry

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AB - The present work compared the effects of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC-HCl) and ultraviolet (UV)- or blue light-activated riboflavin cross-linking agents on resin–dentin micro-tensile bond strength and nanoleakage in bonds produced using a two-step, etch-and-rinse adhesive after three storage intervals (24 h, 6 months, and 12 months). Forty eight extracted human third molars were used to investigate micro-tensile bond strength and interfacial nanoleakage in resin–dentin bonds created using Adper Single Bond 2, with or without pretreatment of acid-etched dentin surfaces. Either 0.5 M EDC-HCl or 1% riboflavin-5-phosphate activated by blue or UV light were used as cross-linking agents. Samples were evaluated after storage for 24 h, 6 months, or 12 months in distilled water at 37 °C. Statistical analyses revealed that 12 months of storage resulted in significant decreases in the bond strength of the controls (p < 0.003), with significant increases in their silver nanoleakage (p < 0.05), compared with the groups subjected to dentin pretreatment with either EDC-HCl or light-activated 1% riboflavin. Despite the significant drop in bond strength after 6 months’ storage in all experimental groups compared with the 24-h bond strength (p < 0.05), there was a further non-significant drop in bond strength after 12 months in samples treated with EDC-HCl and UV-activated 1% riboflavin (p > 0.05). Dental collagen cross-linking induced by UV- or blue light-activated 1% riboflavin or EDC-HCl enhanced the durability and strength of the resin–dentin bond.

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