Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus

Kostas N. Fountas, Eftychia Z. Kapsalaki, Konstantinos N. Paterakis, Gregory P. Lee, Georgios M. Hadjigeorgiou

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Abstract

Objective: The purpose of our study was to evaluate the results of endoscopic third ventriculostomy (ETV) in the management of patients with idiopathic normal pressure hydrocephalus (INPH). Methods: Our prospective study included seven patients (five men and two women; ages ranging between 68 and 78 years) with two or more typical NPH symptoms of short duration (<6 months), with no other morbidity factors, with a Mini-Mental State Examination (MMSE) score ≥18, aqueductal cerebrospinal fluid (CSF) stroke volume ≥42 μL, and positive lumbar drain test. The etiology of NPH was idiopathic in all of these cases. Their preoperative work-up included brain magnetic resonance imaging (MRI) and cine-MR, MMSE test, and CSF lumbar drain test, in all cases. The clinical status of all participants was graded using the Japanese intractable hydrocephalus system. An ETV was performed in all participants. Follow-up included periodic clinical evaluations, MMSE, and MRI with cine-MR studies. The follow-up time range was 12-72 months. Results: The mean postoperative clinical grade was 3.1, while the preoperative was 6.1. Gait disturbance and urinary incontinence were the most responsive symptoms. The mean postoperative MMSE score was 23.6, while the preoperative score was 20.3. The mean postoperative aqueductal CSF stroke volume, 6 months after the procedure, was 31.6 μL, while the preoperative volume was 48.8 μL. Conclusions: ETV may be a safe alternative surgical option for a limited number of carefully selected INPH patients.

Original languageEnglish (US)
Title of host publicationHydrocephalus
Subtitle of host publicationSelected Papers from the International Workshop in Crete, 2010
PublisherSpringer-Verlag Wien
Pages129-133
Number of pages5
Edition113
ISBN (Print)9783709109229
DOIs
StatePublished - Jan 1 2012

Publication series

NameActa Neurochirurgica, Supplementum
Number113
ISSN (Print)0065-1419
ISSN (Electronic)0001-6268

Fingerprint

Ventriculostomy
Normal Pressure Hydrocephalus
Cine Magnetic Resonance Imaging
Cerebrospinal Fluid
Stroke Volume
Urinary Incontinence
Hydrocephalus
Gait
Therapeutics
Prospective Studies
Morbidity
Brain

Keywords

  • Complication
  • Endoscopic
  • Hydrocephalus
  • Normal pressure
  • Outcome
  • Third ventriculostomy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Fountas, K. N., Kapsalaki, E. Z., Paterakis, K. N., Lee, G. P., & Hadjigeorgiou, G. M. (2012). Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus. In Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010 (113 ed., pp. 129-133). (Acta Neurochirurgica, Supplementum; No. 113). Springer-Verlag Wien. https://doi.org/10.1007/978-3-7091-0923-6_26

Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus. / Fountas, Kostas N.; Kapsalaki, Eftychia Z.; Paterakis, Konstantinos N.; Lee, Gregory P.; Hadjigeorgiou, Georgios M.

Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010. 113. ed. Springer-Verlag Wien, 2012. p. 129-133 (Acta Neurochirurgica, Supplementum; No. 113).

Research output: Chapter in Book/Report/Conference proceedingChapter

Fountas, KN, Kapsalaki, EZ, Paterakis, KN, Lee, GP & Hadjigeorgiou, GM 2012, Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus. in Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010. 113 edn, Acta Neurochirurgica, Supplementum, no. 113, Springer-Verlag Wien, pp. 129-133. https://doi.org/10.1007/978-3-7091-0923-6_26
Fountas KN, Kapsalaki EZ, Paterakis KN, Lee GP, Hadjigeorgiou GM. Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus. In Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010. 113 ed. Springer-Verlag Wien. 2012. p. 129-133. (Acta Neurochirurgica, Supplementum; 113). https://doi.org/10.1007/978-3-7091-0923-6_26
Fountas, Kostas N. ; Kapsalaki, Eftychia Z. ; Paterakis, Konstantinos N. ; Lee, Gregory P. ; Hadjigeorgiou, Georgios M. / Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus. Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010. 113. ed. Springer-Verlag Wien, 2012. pp. 129-133 (Acta Neurochirurgica, Supplementum; 113).
@inbook{459e579de36a4f3f995862d63c21862e,
title = "Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus",
abstract = "Objective: The purpose of our study was to evaluate the results of endoscopic third ventriculostomy (ETV) in the management of patients with idiopathic normal pressure hydrocephalus (INPH). Methods: Our prospective study included seven patients (five men and two women; ages ranging between 68 and 78 years) with two or more typical NPH symptoms of short duration (<6 months), with no other morbidity factors, with a Mini-Mental State Examination (MMSE) score ≥18, aqueductal cerebrospinal fluid (CSF) stroke volume ≥42 μL, and positive lumbar drain test. The etiology of NPH was idiopathic in all of these cases. Their preoperative work-up included brain magnetic resonance imaging (MRI) and cine-MR, MMSE test, and CSF lumbar drain test, in all cases. The clinical status of all participants was graded using the Japanese intractable hydrocephalus system. An ETV was performed in all participants. Follow-up included periodic clinical evaluations, MMSE, and MRI with cine-MR studies. The follow-up time range was 12-72 months. Results: The mean postoperative clinical grade was 3.1, while the preoperative was 6.1. Gait disturbance and urinary incontinence were the most responsive symptoms. The mean postoperative MMSE score was 23.6, while the preoperative score was 20.3. The mean postoperative aqueductal CSF stroke volume, 6 months after the procedure, was 31.6 μL, while the preoperative volume was 48.8 μL. Conclusions: ETV may be a safe alternative surgical option for a limited number of carefully selected INPH patients.",
keywords = "Complication, Endoscopic, Hydrocephalus, Normal pressure, Outcome, Third ventriculostomy",
author = "Fountas, {Kostas N.} and Kapsalaki, {Eftychia Z.} and Paterakis, {Konstantinos N.} and Lee, {Gregory P.} and Hadjigeorgiou, {Georgios M.}",
year = "2012",
month = "1",
day = "1",
doi = "10.1007/978-3-7091-0923-6_26",
language = "English (US)",
isbn = "9783709109229",
series = "Acta Neurochirurgica, Supplementum",
publisher = "Springer-Verlag Wien",
number = "113",
pages = "129--133",
booktitle = "Hydrocephalus",
edition = "113",

}

TY - CHAP

T1 - Role of endoscopic third ventriculostomy in treatment of selected patients with normal pressure hydrocephalus

AU - Fountas, Kostas N.

AU - Kapsalaki, Eftychia Z.

AU - Paterakis, Konstantinos N.

AU - Lee, Gregory P.

AU - Hadjigeorgiou, Georgios M.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Objective: The purpose of our study was to evaluate the results of endoscopic third ventriculostomy (ETV) in the management of patients with idiopathic normal pressure hydrocephalus (INPH). Methods: Our prospective study included seven patients (five men and two women; ages ranging between 68 and 78 years) with two or more typical NPH symptoms of short duration (<6 months), with no other morbidity factors, with a Mini-Mental State Examination (MMSE) score ≥18, aqueductal cerebrospinal fluid (CSF) stroke volume ≥42 μL, and positive lumbar drain test. The etiology of NPH was idiopathic in all of these cases. Their preoperative work-up included brain magnetic resonance imaging (MRI) and cine-MR, MMSE test, and CSF lumbar drain test, in all cases. The clinical status of all participants was graded using the Japanese intractable hydrocephalus system. An ETV was performed in all participants. Follow-up included periodic clinical evaluations, MMSE, and MRI with cine-MR studies. The follow-up time range was 12-72 months. Results: The mean postoperative clinical grade was 3.1, while the preoperative was 6.1. Gait disturbance and urinary incontinence were the most responsive symptoms. The mean postoperative MMSE score was 23.6, while the preoperative score was 20.3. The mean postoperative aqueductal CSF stroke volume, 6 months after the procedure, was 31.6 μL, while the preoperative volume was 48.8 μL. Conclusions: ETV may be a safe alternative surgical option for a limited number of carefully selected INPH patients.

AB - Objective: The purpose of our study was to evaluate the results of endoscopic third ventriculostomy (ETV) in the management of patients with idiopathic normal pressure hydrocephalus (INPH). Methods: Our prospective study included seven patients (five men and two women; ages ranging between 68 and 78 years) with two or more typical NPH symptoms of short duration (<6 months), with no other morbidity factors, with a Mini-Mental State Examination (MMSE) score ≥18, aqueductal cerebrospinal fluid (CSF) stroke volume ≥42 μL, and positive lumbar drain test. The etiology of NPH was idiopathic in all of these cases. Their preoperative work-up included brain magnetic resonance imaging (MRI) and cine-MR, MMSE test, and CSF lumbar drain test, in all cases. The clinical status of all participants was graded using the Japanese intractable hydrocephalus system. An ETV was performed in all participants. Follow-up included periodic clinical evaluations, MMSE, and MRI with cine-MR studies. The follow-up time range was 12-72 months. Results: The mean postoperative clinical grade was 3.1, while the preoperative was 6.1. Gait disturbance and urinary incontinence were the most responsive symptoms. The mean postoperative MMSE score was 23.6, while the preoperative score was 20.3. The mean postoperative aqueductal CSF stroke volume, 6 months after the procedure, was 31.6 μL, while the preoperative volume was 48.8 μL. Conclusions: ETV may be a safe alternative surgical option for a limited number of carefully selected INPH patients.

KW - Complication

KW - Endoscopic

KW - Hydrocephalus

KW - Normal pressure

KW - Outcome

KW - Third ventriculostomy

UR - http://www.scopus.com/inward/record.url?scp=84555187127&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84555187127&partnerID=8YFLogxK

U2 - 10.1007/978-3-7091-0923-6_26

DO - 10.1007/978-3-7091-0923-6_26

M3 - Chapter

C2 - 22116438

AN - SCOPUS:84555187127

SN - 9783709109229

T3 - Acta Neurochirurgica, Supplementum

SP - 129

EP - 133

BT - Hydrocephalus

PB - Springer-Verlag Wien

ER -