Sarcopenia defined by a computed tomography estimate of the psoas muscle area does not predict frailty in geriatric trauma patients

Ashley Mccusker, Muhammad Khan, Narong Kulvatunyou, Muhammad Zeeshan, Joseph V. Sakran, Haya Hayek, Terence OKeeffe, Mohammad Hamidi, Andrew Tang, Bellal Joseph

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: The aim of our study was to assess the correlation between frailty & sarcopenia and impact of each condition on outcomes in geriatric trauma patients. Methods: We performed a four-year (2013–2016) secondary analysis of our prospectively maintained frailty database and included all trauma patients age ≥65 y who had CT-abdomen. Trauma-Specific-Frailty-Index (TSFI) was used to calculate frailty. Patients were classified as non-frail or frail. Sarcopenia was defined as the lowest sex-specific-quartile of total-psoas-index (TPI). Outcome measures included in-hospital complications, mortality and adverse disposition. Results: 325 patients were included in the study, 36% (n = 117) were frail and 24.9% (n = 81) had sarcopenia. There was a weak correlation between frailty and sarcopenia (R2 = 0.04). The overall rate of complications and mortality was 19.4% and 7.7% respectively. On regression analysis, after controlling for possible confounding variables and frailty status, sarcopenia was associated with adverse disposition (OR:1.41,p = 0.01). However, it was not associated with in-hospital complications (OR:1.21,p = 0.54) or in-hospital mortality (OR:1.12,p = 0.73). Conclusion: Sarcopenia as an individual marker might not be an effective screening tool for risk assessment in geriatric-trauma patients. Frailty assessment should be a part of risk assessment and prognostication.

Original languageEnglish (US)
Pages (from-to)261-265
Number of pages5
JournalAmerican Journal of Surgery
Volume218
Issue number2
DOIs
StatePublished - Aug 1 2019

Fingerprint

Psoas Muscles
Sarcopenia
Geriatrics
Tomography
Wounds and Injuries
Hospital Mortality
Confounding Factors (Epidemiology)
Abdomen
Regression Analysis
Outcome Assessment (Health Care)
Databases
Mortality

Keywords

  • Frailty
  • Geriatric trauma
  • Geriatrics
  • Level II
  • Prognostic studies
  • Sarcopenia

ASJC Scopus subject areas

  • Surgery

Cite this

Sarcopenia defined by a computed tomography estimate of the psoas muscle area does not predict frailty in geriatric trauma patients. / Mccusker, Ashley; Khan, Muhammad; Kulvatunyou, Narong; Zeeshan, Muhammad; Sakran, Joseph V.; Hayek, Haya; OKeeffe, Terence; Hamidi, Mohammad; Tang, Andrew; Joseph, Bellal.

In: American Journal of Surgery, Vol. 218, No. 2, 01.08.2019, p. 261-265.

Research output: Contribution to journalArticle

Mccusker, A, Khan, M, Kulvatunyou, N, Zeeshan, M, Sakran, JV, Hayek, H, OKeeffe, T, Hamidi, M, Tang, A & Joseph, B 2019, 'Sarcopenia defined by a computed tomography estimate of the psoas muscle area does not predict frailty in geriatric trauma patients', American Journal of Surgery, vol. 218, no. 2, pp. 261-265. https://doi.org/10.1016/j.amjsurg.2018.07.024
Mccusker, Ashley ; Khan, Muhammad ; Kulvatunyou, Narong ; Zeeshan, Muhammad ; Sakran, Joseph V. ; Hayek, Haya ; OKeeffe, Terence ; Hamidi, Mohammad ; Tang, Andrew ; Joseph, Bellal. / Sarcopenia defined by a computed tomography estimate of the psoas muscle area does not predict frailty in geriatric trauma patients. In: American Journal of Surgery. 2019 ; Vol. 218, No. 2. pp. 261-265.
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AU - Mccusker, Ashley

AU - Khan, Muhammad

AU - Kulvatunyou, Narong

AU - Zeeshan, Muhammad

AU - Sakran, Joseph V.

AU - Hayek, Haya

AU - OKeeffe, Terence

AU - Hamidi, Mohammad

AU - Tang, Andrew

AU - Joseph, Bellal

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N2 - Introduction: The aim of our study was to assess the correlation between frailty & sarcopenia and impact of each condition on outcomes in geriatric trauma patients. Methods: We performed a four-year (2013–2016) secondary analysis of our prospectively maintained frailty database and included all trauma patients age ≥65 y who had CT-abdomen. Trauma-Specific-Frailty-Index (TSFI) was used to calculate frailty. Patients were classified as non-frail or frail. Sarcopenia was defined as the lowest sex-specific-quartile of total-psoas-index (TPI). Outcome measures included in-hospital complications, mortality and adverse disposition. Results: 325 patients were included in the study, 36% (n = 117) were frail and 24.9% (n = 81) had sarcopenia. There was a weak correlation between frailty and sarcopenia (R2 = 0.04). The overall rate of complications and mortality was 19.4% and 7.7% respectively. On regression analysis, after controlling for possible confounding variables and frailty status, sarcopenia was associated with adverse disposition (OR:1.41,p = 0.01). However, it was not associated with in-hospital complications (OR:1.21,p = 0.54) or in-hospital mortality (OR:1.12,p = 0.73). Conclusion: Sarcopenia as an individual marker might not be an effective screening tool for risk assessment in geriatric-trauma patients. Frailty assessment should be a part of risk assessment and prognostication.

AB - Introduction: The aim of our study was to assess the correlation between frailty & sarcopenia and impact of each condition on outcomes in geriatric trauma patients. Methods: We performed a four-year (2013–2016) secondary analysis of our prospectively maintained frailty database and included all trauma patients age ≥65 y who had CT-abdomen. Trauma-Specific-Frailty-Index (TSFI) was used to calculate frailty. Patients were classified as non-frail or frail. Sarcopenia was defined as the lowest sex-specific-quartile of total-psoas-index (TPI). Outcome measures included in-hospital complications, mortality and adverse disposition. Results: 325 patients were included in the study, 36% (n = 117) were frail and 24.9% (n = 81) had sarcopenia. There was a weak correlation between frailty and sarcopenia (R2 = 0.04). The overall rate of complications and mortality was 19.4% and 7.7% respectively. On regression analysis, after controlling for possible confounding variables and frailty status, sarcopenia was associated with adverse disposition (OR:1.41,p = 0.01). However, it was not associated with in-hospital complications (OR:1.21,p = 0.54) or in-hospital mortality (OR:1.12,p = 0.73). Conclusion: Sarcopenia as an individual marker might not be an effective screening tool for risk assessment in geriatric-trauma patients. Frailty assessment should be a part of risk assessment and prognostication.

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KW - Geriatrics

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