Scan findings of various myocardial spect agents in a case of amyloid polyneuropathy with suspected myocardial involvement

Ali Syed Arbab, Kiyoshi Koizumi, Keiji Toyama, Takao Arai, Tatsuya Yoshitomi, Tsutomu Araki

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A 31-year-old male having familial amyloid polyneuropathy underwent a Tc-99m(V)-DMSA study to evaluate the myocardial involvement. The patient also underwent Tl-201, I-123-BMIPP and I-123-MIBG myocardial SPECT studies to evaluate blood perfusion, fatty acid metabolism and sympathetic function of the heart, respectively. Tc-99m(V)-DMSA SPECT showed uptake to the myocardium indicating myocardial involvement of amyloidosis. Both Tl-201 and I-123- BMIPP studies showed normal uptake indicating normal blood perfusion and fatty acid metabolism but I-123-MIBG SPECT showed no uptake to the heart, indicating severe impairment of sympathetic function.

Original languageEnglish (US)
Pages (from-to)139-141
Number of pages3
JournalAnnals of Nuclear Medicine
Volume11
Issue number2
DOIs
StatePublished - May 1997
Externally publishedYes

Keywords

  • Amyloidosis
  • I-123-BMIPP
  • I-123-MIBG
  • Tc-99m(V)-DMSA
  • Tl-201

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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