Screening of seven putative 45,X subjects with deoxyribonucleic acid probes to detect low-level mosaicism for Y cell lines

Sandra P.T. Tho, Ali Behzadian, Paul G. McDonough

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The frequency of monosomy X in cytogenetically abnormal abortion material (10% to 15%) suggests that viable 45,X subjects might have covert mosaicism for X or Y cell lines. The deoxyribonucleic acid samples from seven 45,X subjects with Tumer syndrome were examined with three Y-specific deoxyribonucleic acid probes. Successive hybridizations with each of these three sensitive deoxyribonucleic acid probes did not reveal any Y-specific band.

Original languageEnglish (US)
Pages (from-to)59-60
Number of pages2
JournalAmerican journal of obstetrics and gynecology
Volume162
Issue number1
DOIs
Publication statusPublished - Jan 1990

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Keywords

  • 45,X
  • 4B2
  • Y deoxyribonucleic probes
  • Y97
  • pS4

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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