Selective downregulation of endothelin-B receptors in diabetic African-American patients

Medicine & Life Sciences

• Endothelin B Receptors 100%
• African Americans 64%
• 2-(2-(1-phenyl-4-piperazynyl)ethyl)-1,2,3,4-tetrahydro-beta-carboline-1-spiro-4'-N'-benzylpiperidine 59%
• Down-Regulation 48%
• Endothelins 32%
• Endothelin-1 29%
• Blood Vessels 24%
• Tibial Arteries 19%
• Endothelin Receptors 18%
• Endothelin A Receptors 18%
• Nitroprusside 15%
• Reverse Transcriptase Polymerase Chain Reaction 14%
• Amputation 13%
• Lower Extremity 11%
• Arteries 10%
• Phenotype 8%
• Gene Expression 8%
• Messenger RNA 7%
• Incidence 6%
• Population 5%