Semiqualitative visual and quantitative morphometric evaluations of reduced scan time and wide-beam reconstruction in rest-gated stress SPECT myocardial perfusion imaging

Danny Basso, Gregory Passmore, Michael Holman, Ward Rogers, Leslie Walters, Thomas Zecchin, Jayme Butler

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

SPECT myocardial perfusion imaging (MPI) now accounts for well over 90% of all MPI studies performed in the United States. A means of reducing the acquisition time while maintaining diagnostic-quality images would be beneficial for both patients and nuclear cardiology clinics. Wide-beam reconstruction (WBR) is a processing algorithm that attempts to address the challenge of obtaining diagnostic-quality images with shorter counting times. This study was designed to incorporate semiqualitative assessments (physician rankings of image parameters) into quantitative assessments (morphologic measurements), as other researchers have done, in an effort to compare filtered backprojection (FBP)-the gold standard-with WBR. Methods: Forty-seven MPI studies (from 34 men and 13 women) were masked to 3 physicians who qualitatively rated the images for image quality,myocardial normality, lesion reversibility, and treatment recommendation on a scale of 1-5, with 1 representing "good" and 5 representing "poor." Quantitative values for summed stress scores, summed rest scores, summed difference scores (SDS), end-diastolic volume, end-systolic volume, and the ejection fraction were calculated and reported. Results: The semiqualitative analyses of image interpretation indicated that WBR yielded significant improvements over FBP in image quality and showed very good to moderate agreement with FBP among physicians formyocardial normality, lesion reversibility, and treatment recommendation. The quantitative analyses of the morphometric values representing myocardial perfusion, through SDS comparisons, were equivalent for the 2 reconstruction methods. Regression analysis indicated that WBR seemed to underestimate the gated stress-derived FBP ejection fraction by 9%-10%. Conclusion: Overall, the WBR method was equivalent or superior to the FBP reconstruction method for MPI with a rest-gated stress sameday protocol in terms of image quality, interpretation, and SDS. Additionally, the advantage of patient comfort derived fromshorter imaging times should help reduce motion artifacts and repeat acquisitions as well as enhance patient care and throughput.

Original languageEnglish (US)
Pages (from-to)233-239
Number of pages7
JournalJournal of Nuclear Medicine Technology
Volume37
Issue number4
DOIs
StatePublished - Dec 1 2009

Fingerprint

Myocardial Perfusion Imaging
Single-Photon Emission-Computed Tomography
Physicians
Cardiology
Artifacts
Patient Care
Perfusion
Regression Analysis
Research Personnel
Therapeutics

Keywords

  • Filtered backprojection
  • Myocardial perfusion imaging
  • Wide-beam reconstruction

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Semiqualitative visual and quantitative morphometric evaluations of reduced scan time and wide-beam reconstruction in rest-gated stress SPECT myocardial perfusion imaging. / Basso, Danny; Passmore, Gregory; Holman, Michael; Rogers, Ward; Walters, Leslie; Zecchin, Thomas; Butler, Jayme.

In: Journal of Nuclear Medicine Technology, Vol. 37, No. 4, 01.12.2009, p. 233-239.

Research output: Contribution to journalArticle

@article{aff03eaa7ff541168220ba13cfde8e2b,
title = "Semiqualitative visual and quantitative morphometric evaluations of reduced scan time and wide-beam reconstruction in rest-gated stress SPECT myocardial perfusion imaging",
abstract = "SPECT myocardial perfusion imaging (MPI) now accounts for well over 90{\%} of all MPI studies performed in the United States. A means of reducing the acquisition time while maintaining diagnostic-quality images would be beneficial for both patients and nuclear cardiology clinics. Wide-beam reconstruction (WBR) is a processing algorithm that attempts to address the challenge of obtaining diagnostic-quality images with shorter counting times. This study was designed to incorporate semiqualitative assessments (physician rankings of image parameters) into quantitative assessments (morphologic measurements), as other researchers have done, in an effort to compare filtered backprojection (FBP)-the gold standard-with WBR. Methods: Forty-seven MPI studies (from 34 men and 13 women) were masked to 3 physicians who qualitatively rated the images for image quality,myocardial normality, lesion reversibility, and treatment recommendation on a scale of 1-5, with 1 representing {"}good{"} and 5 representing {"}poor.{"} Quantitative values for summed stress scores, summed rest scores, summed difference scores (SDS), end-diastolic volume, end-systolic volume, and the ejection fraction were calculated and reported. Results: The semiqualitative analyses of image interpretation indicated that WBR yielded significant improvements over FBP in image quality and showed very good to moderate agreement with FBP among physicians formyocardial normality, lesion reversibility, and treatment recommendation. The quantitative analyses of the morphometric values representing myocardial perfusion, through SDS comparisons, were equivalent for the 2 reconstruction methods. Regression analysis indicated that WBR seemed to underestimate the gated stress-derived FBP ejection fraction by 9{\%}-10{\%}. Conclusion: Overall, the WBR method was equivalent or superior to the FBP reconstruction method for MPI with a rest-gated stress sameday protocol in terms of image quality, interpretation, and SDS. Additionally, the advantage of patient comfort derived fromshorter imaging times should help reduce motion artifacts and repeat acquisitions as well as enhance patient care and throughput.",
keywords = "Filtered backprojection, Myocardial perfusion imaging, Wide-beam reconstruction",
author = "Danny Basso and Gregory Passmore and Michael Holman and Ward Rogers and Leslie Walters and Thomas Zecchin and Jayme Butler",
year = "2009",
month = "12",
day = "1",
doi = "10.2967/jnmt.109.063644",
language = "English (US)",
volume = "37",
pages = "233--239",
journal = "Journal of Nuclear Medicine Technology",
issn = "0091-4916",
publisher = "Society of Nuclear Medicine Inc.",
number = "4",

}

TY - JOUR

T1 - Semiqualitative visual and quantitative morphometric evaluations of reduced scan time and wide-beam reconstruction in rest-gated stress SPECT myocardial perfusion imaging

AU - Basso, Danny

AU - Passmore, Gregory

AU - Holman, Michael

AU - Rogers, Ward

AU - Walters, Leslie

AU - Zecchin, Thomas

AU - Butler, Jayme

PY - 2009/12/1

Y1 - 2009/12/1

N2 - SPECT myocardial perfusion imaging (MPI) now accounts for well over 90% of all MPI studies performed in the United States. A means of reducing the acquisition time while maintaining diagnostic-quality images would be beneficial for both patients and nuclear cardiology clinics. Wide-beam reconstruction (WBR) is a processing algorithm that attempts to address the challenge of obtaining diagnostic-quality images with shorter counting times. This study was designed to incorporate semiqualitative assessments (physician rankings of image parameters) into quantitative assessments (morphologic measurements), as other researchers have done, in an effort to compare filtered backprojection (FBP)-the gold standard-with WBR. Methods: Forty-seven MPI studies (from 34 men and 13 women) were masked to 3 physicians who qualitatively rated the images for image quality,myocardial normality, lesion reversibility, and treatment recommendation on a scale of 1-5, with 1 representing "good" and 5 representing "poor." Quantitative values for summed stress scores, summed rest scores, summed difference scores (SDS), end-diastolic volume, end-systolic volume, and the ejection fraction were calculated and reported. Results: The semiqualitative analyses of image interpretation indicated that WBR yielded significant improvements over FBP in image quality and showed very good to moderate agreement with FBP among physicians formyocardial normality, lesion reversibility, and treatment recommendation. The quantitative analyses of the morphometric values representing myocardial perfusion, through SDS comparisons, were equivalent for the 2 reconstruction methods. Regression analysis indicated that WBR seemed to underestimate the gated stress-derived FBP ejection fraction by 9%-10%. Conclusion: Overall, the WBR method was equivalent or superior to the FBP reconstruction method for MPI with a rest-gated stress sameday protocol in terms of image quality, interpretation, and SDS. Additionally, the advantage of patient comfort derived fromshorter imaging times should help reduce motion artifacts and repeat acquisitions as well as enhance patient care and throughput.

AB - SPECT myocardial perfusion imaging (MPI) now accounts for well over 90% of all MPI studies performed in the United States. A means of reducing the acquisition time while maintaining diagnostic-quality images would be beneficial for both patients and nuclear cardiology clinics. Wide-beam reconstruction (WBR) is a processing algorithm that attempts to address the challenge of obtaining diagnostic-quality images with shorter counting times. This study was designed to incorporate semiqualitative assessments (physician rankings of image parameters) into quantitative assessments (morphologic measurements), as other researchers have done, in an effort to compare filtered backprojection (FBP)-the gold standard-with WBR. Methods: Forty-seven MPI studies (from 34 men and 13 women) were masked to 3 physicians who qualitatively rated the images for image quality,myocardial normality, lesion reversibility, and treatment recommendation on a scale of 1-5, with 1 representing "good" and 5 representing "poor." Quantitative values for summed stress scores, summed rest scores, summed difference scores (SDS), end-diastolic volume, end-systolic volume, and the ejection fraction were calculated and reported. Results: The semiqualitative analyses of image interpretation indicated that WBR yielded significant improvements over FBP in image quality and showed very good to moderate agreement with FBP among physicians formyocardial normality, lesion reversibility, and treatment recommendation. The quantitative analyses of the morphometric values representing myocardial perfusion, through SDS comparisons, were equivalent for the 2 reconstruction methods. Regression analysis indicated that WBR seemed to underestimate the gated stress-derived FBP ejection fraction by 9%-10%. Conclusion: Overall, the WBR method was equivalent or superior to the FBP reconstruction method for MPI with a rest-gated stress sameday protocol in terms of image quality, interpretation, and SDS. Additionally, the advantage of patient comfort derived fromshorter imaging times should help reduce motion artifacts and repeat acquisitions as well as enhance patient care and throughput.

KW - Filtered backprojection

KW - Myocardial perfusion imaging

KW - Wide-beam reconstruction

UR - http://www.scopus.com/inward/record.url?scp=73249115178&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=73249115178&partnerID=8YFLogxK

U2 - 10.2967/jnmt.109.063644

DO - 10.2967/jnmt.109.063644

M3 - Article

C2 - 19914980

AN - SCOPUS:73249115178

VL - 37

SP - 233

EP - 239

JO - Journal of Nuclear Medicine Technology

JF - Journal of Nuclear Medicine Technology

SN - 0091-4916

IS - 4

ER -