Sensitivity and specificity of asthma definitions and symptoms used in a survey of childhood asthma

Christine L.M. Joseph, Betsy Foxman, Frederick E. Leickly, Edward Peterson, Dennis Randall Ownby

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

We compared the ability of definitions/symptoms of asthma to identify urban, elementary schoolchildren with physician-diagnosed asthma and bronchial hyperresponsiveness (BHR) post-exercise challenge. Definitions of asthma from the literature were compared, including American Thoracic Society (ATS) and British Medical Research Council (BMRC) definitions. Modified ATS had the highest sensitivity (77%), whereas BMRC had the highest specificity (99%). The most sensitive symptom was 'wheeze with cold' (89%). The most specific symptoms were 'medication required,' and 'breathing normal between attacks' (95%). Definitions and symptoms were poor predictors of BHR. Researchers can use these estimates in selecting and defining specific populations of children with asthma.

Original languageEnglish (US)
Pages (from-to)565-573
Number of pages9
JournalJournal of Asthma
Volume36
Issue number7
DOIs
StatePublished - Jan 1 1999

Fingerprint

Asthma
Sensitivity and Specificity
Biomedical Research
Respiration
Thorax
Research Personnel
Exercise
Physicians
Surveys and Questionnaires
Population

Keywords

  • Asthma
  • BHR
  • Physician-diagnosed asthma
  • Screening
  • Symptoms
  • Urban schoolchildren

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

Sensitivity and specificity of asthma definitions and symptoms used in a survey of childhood asthma. / Joseph, Christine L.M.; Foxman, Betsy; Leickly, Frederick E.; Peterson, Edward; Ownby, Dennis Randall.

In: Journal of Asthma, Vol. 36, No. 7, 01.01.1999, p. 565-573.

Research output: Contribution to journalArticle

Joseph, Christine L.M. ; Foxman, Betsy ; Leickly, Frederick E. ; Peterson, Edward ; Ownby, Dennis Randall. / Sensitivity and specificity of asthma definitions and symptoms used in a survey of childhood asthma. In: Journal of Asthma. 1999 ; Vol. 36, No. 7. pp. 565-573.
@article{0a47afbef8a84d3f83e42b48275de655,
title = "Sensitivity and specificity of asthma definitions and symptoms used in a survey of childhood asthma",
abstract = "We compared the ability of definitions/symptoms of asthma to identify urban, elementary schoolchildren with physician-diagnosed asthma and bronchial hyperresponsiveness (BHR) post-exercise challenge. Definitions of asthma from the literature were compared, including American Thoracic Society (ATS) and British Medical Research Council (BMRC) definitions. Modified ATS had the highest sensitivity (77{\%}), whereas BMRC had the highest specificity (99{\%}). The most sensitive symptom was 'wheeze with cold' (89{\%}). The most specific symptoms were 'medication required,' and 'breathing normal between attacks' (95{\%}). Definitions and symptoms were poor predictors of BHR. Researchers can use these estimates in selecting and defining specific populations of children with asthma.",
keywords = "Asthma, BHR, Physician-diagnosed asthma, Screening, Symptoms, Urban schoolchildren",
author = "Joseph, {Christine L.M.} and Betsy Foxman and Leickly, {Frederick E.} and Edward Peterson and Ownby, {Dennis Randall}",
year = "1999",
month = "1",
day = "1",
doi = "10.3109/02770909909087293",
language = "English (US)",
volume = "36",
pages = "565--573",
journal = "Journal of Asthma",
issn = "0277-0903",
publisher = "Informa Healthcare",
number = "7",

}

TY - JOUR

T1 - Sensitivity and specificity of asthma definitions and symptoms used in a survey of childhood asthma

AU - Joseph, Christine L.M.

AU - Foxman, Betsy

AU - Leickly, Frederick E.

AU - Peterson, Edward

AU - Ownby, Dennis Randall

PY - 1999/1/1

Y1 - 1999/1/1

N2 - We compared the ability of definitions/symptoms of asthma to identify urban, elementary schoolchildren with physician-diagnosed asthma and bronchial hyperresponsiveness (BHR) post-exercise challenge. Definitions of asthma from the literature were compared, including American Thoracic Society (ATS) and British Medical Research Council (BMRC) definitions. Modified ATS had the highest sensitivity (77%), whereas BMRC had the highest specificity (99%). The most sensitive symptom was 'wheeze with cold' (89%). The most specific symptoms were 'medication required,' and 'breathing normal between attacks' (95%). Definitions and symptoms were poor predictors of BHR. Researchers can use these estimates in selecting and defining specific populations of children with asthma.

AB - We compared the ability of definitions/symptoms of asthma to identify urban, elementary schoolchildren with physician-diagnosed asthma and bronchial hyperresponsiveness (BHR) post-exercise challenge. Definitions of asthma from the literature were compared, including American Thoracic Society (ATS) and British Medical Research Council (BMRC) definitions. Modified ATS had the highest sensitivity (77%), whereas BMRC had the highest specificity (99%). The most sensitive symptom was 'wheeze with cold' (89%). The most specific symptoms were 'medication required,' and 'breathing normal between attacks' (95%). Definitions and symptoms were poor predictors of BHR. Researchers can use these estimates in selecting and defining specific populations of children with asthma.

KW - Asthma

KW - BHR

KW - Physician-diagnosed asthma

KW - Screening

KW - Symptoms

KW - Urban schoolchildren

UR - http://www.scopus.com/inward/record.url?scp=0032843446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032843446&partnerID=8YFLogxK

U2 - 10.3109/02770909909087293

DO - 10.3109/02770909909087293

M3 - Article

C2 - 10524539

AN - SCOPUS:0032843446

VL - 36

SP - 565

EP - 573

JO - Journal of Asthma

JF - Journal of Asthma

SN - 0277-0903

IS - 7

ER -