Sequential assessment of troponin in the diagnosis of myocardial infarction.

Brandon Edwards, Irsha Washington, Lester G Pretlow, Gregory G Passmore, James Dias, Scott Wise

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

According to the American Heart Association, cardiovascular disease accounts for more than one third of all deaths in the United States. 1 The purpose of this retrospective case-control study was to determine which sample taken in a sequential draw was most important in diagnosing an acute myocardial infarction (AMI). One-hundred subjects were selected from a convenience sample. The "risk" of AMI diagnosis was modeled using binary multiple logistic regression. Overall, 78% (39 out of 50 cases) were diagnosed with an AMI at Tinitiai. Clearly, the initial cTnI assay is the most critical of the four sequential time points for the accurate assessment of the presence or absence of an AMI. Most importantly, sequential troponin testing increased the ability to diagnose AMI by 10-fold.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalClinical laboratory science : journal of the American Society for Medical Technology
Volume26
Issue number2
StatePublished - Mar 1 2013
Externally publishedYes

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Troponin
Myocardial Infarction
Logistics
Assays
Testing
Case-Control Studies
Cardiovascular Diseases
Logistic Models

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Sequential assessment of troponin in the diagnosis of myocardial infarction. / Edwards, Brandon; Washington, Irsha; Pretlow, Lester G; Passmore, Gregory G; Dias, James; Wise, Scott.

In: Clinical laboratory science : journal of the American Society for Medical Technology, Vol. 26, No. 2, 01.03.2013, p. 95-99.

Research output: Contribution to journalArticle

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