Abstract
Teratogenic effects of polymethylmethacrylate cement at levels used during routine orthopaedic procedures have never been reported, however the hypothetical risk remains a major concern among female surgeons. Our aim was to determine if methyl methacrylate is detectible in the serum during routine cement exposure. Methods: Twenty healthy volunteers were exposed during the mixing of polymethylmethacrylate cement in a simulated operating room environment. Forty serum samples were obtained during the expected peak inhalational exposure and levels of methyl methacrylate were assessed utilizing headspace gas chromatography mass spectrometry. Results: Methyl methacrylate was not detected in any of the forty experimental specimens. Conclusions: With a detection level of 0.5 ppm, methyl methacrylate is undetectable in the serum during routine mixing of polymethylmethacrylate cement.
Original language | English (US) |
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Pages (from-to) | 406-409 |
Number of pages | 4 |
Journal | Journal of Arthroplasty |
Volume | 28 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2013 |
Keywords
- Methyl methacrylate
- PMMA
- Polymethylmethacrylate
- Serum
ASJC Scopus subject areas
- Orthopedics and Sports Medicine