Serum prolactin, electrode placement, and the convulsive threshold during ECT

W. Vaughn McCall; Richard D. Weiner; Bernard J. Carroll; Frank E. Shelp; James C. Ritchie; Shirley Austin; Judy Norris

Serum prolactin, electrode placement, and the convulsive threshold during ECT

W. Vaughn McCall, Richard D. Weiner, Bernard J. Carroll, Frank E. Shelp, James C. Ritchie, Shirley Austin, Judy Norris

Research output: Contribution to journal › Article › peer-review

Abstract

This study examines the relationship of serum prolactin changes (ΔPRL) to variations in electrode placement after controlling for differences in the convulsive threshold. Previous studies showing greater release of PRL with bilateral (BL) compared with right unilateral (RUL) electrode placement were conducted without knowledge of the convulsive threshold. Twenty-two patients each received threshold RUL, threshold BL, 2.25 times threshold RUL, and 2.25 times threshold BL ECT. Serum PRL was collected 5 min before and 15 min after each electroconvulsive therapy (ECT). The convulsive threshold was greater for BL than RUL electrode placement. ΔPRL was greater with BL than RUL ECT at comparable relative stimulus intensities. ΔPRL was not correlated with seizure duration or absolute stimulus dose.

Original language	English (US)
Pages (from-to)	81-85
Number of pages	5
Journal	Convulsive Therapy
Volume	12
Issue number	2
State	Published - 1996
Externally published	Yes

Keywords

Electroconvulsive therapy
Electrode placement
Prolactin
Seizure threshold

ASJC Scopus subject areas

Psychiatry and Mental health

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title = "Serum prolactin, electrode placement, and the convulsive threshold during ECT",

abstract = "This study examines the relationship of serum prolactin changes (ΔPRL) to variations in electrode placement after controlling for differences in the convulsive threshold. Previous studies showing greater release of PRL with bilateral (BL) compared with right unilateral (RUL) electrode placement were conducted without knowledge of the convulsive threshold. Twenty-two patients each received threshold RUL, threshold BL, 2.25 times threshold RUL, and 2.25 times threshold BL ECT. Serum PRL was collected 5 min before and 15 min after each electroconvulsive therapy (ECT). The convulsive threshold was greater for BL than RUL electrode placement. ΔPRL was greater with BL than RUL ECT at comparable relative stimulus intensities. ΔPRL was not correlated with seizure duration or absolute stimulus dose.",

keywords = "Electroconvulsive therapy, Electrode placement, Prolactin, Seizure threshold",

author = "McCall, {W. Vaughn} and Weiner, {Richard D.} and Carroll, {Bernard J.} and Shelp, {Frank E.} and Ritchie, {James C.} and Shirley Austin and Judy Norris",

year = "1996",

language = "English (US)",

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pages = "81--85",

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T1 - Serum prolactin, electrode placement, and the convulsive threshold during ECT

AU - McCall, W. Vaughn

AU - Weiner, Richard D.

AU - Carroll, Bernard J.

AU - Shelp, Frank E.

AU - Ritchie, James C.

AU - Austin, Shirley

AU - Norris, Judy

PY - 1996

Y1 - 1996

N2 - This study examines the relationship of serum prolactin changes (ΔPRL) to variations in electrode placement after controlling for differences in the convulsive threshold. Previous studies showing greater release of PRL with bilateral (BL) compared with right unilateral (RUL) electrode placement were conducted without knowledge of the convulsive threshold. Twenty-two patients each received threshold RUL, threshold BL, 2.25 times threshold RUL, and 2.25 times threshold BL ECT. Serum PRL was collected 5 min before and 15 min after each electroconvulsive therapy (ECT). The convulsive threshold was greater for BL than RUL electrode placement. ΔPRL was greater with BL than RUL ECT at comparable relative stimulus intensities. ΔPRL was not correlated with seizure duration or absolute stimulus dose.

AB - This study examines the relationship of serum prolactin changes (ΔPRL) to variations in electrode placement after controlling for differences in the convulsive threshold. Previous studies showing greater release of PRL with bilateral (BL) compared with right unilateral (RUL) electrode placement were conducted without knowledge of the convulsive threshold. Twenty-two patients each received threshold RUL, threshold BL, 2.25 times threshold RUL, and 2.25 times threshold BL ECT. Serum PRL was collected 5 min before and 15 min after each electroconvulsive therapy (ECT). The convulsive threshold was greater for BL than RUL electrode placement. ΔPRL was greater with BL than RUL ECT at comparable relative stimulus intensities. ΔPRL was not correlated with seizure duration or absolute stimulus dose.

KW - Electroconvulsive therapy

KW - Electrode placement

KW - Prolactin

KW - Seizure threshold

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