Sex Differences in Gulf War Illness

A Reanalysis of Data From the CDC Air Force Study Using CDC and Modified Kansas Case Definitions

Vahe Heboyan, Maxine H. Krengel, Kimberly Sullivan, Stacey Iobst, Nancy Klimas, Candy Wilson, Steven Scott Coughlin

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: Estimate and compare the prevalence of Gulf War Illness (GWI) in male and female Gulf War veterans using Centers for Disease Control and Prevention (CDC) and modified Kansas case definitions. METHODS: Data from the landmark CDC Air Force Study of GW Air Force veterans is used. RESULTS: Nearly half of the deployed veterans met the GWI CDC case definition compared with 14% of non-deployed veterans. Only 29% met the definition using the modified Kansas criteria compared with 8% of non-deployed veterans. Deployed veterans and female veterans exhibited significantly higher GWI risk. Female GW veterans had higher rates of severe and mild-to-moderate cases of GWI. CONCLUSION: Results suggest increased GWI rates based on CDC and modified Kansas criteria among deployed and female veterans. Further research is needed to examine the chronic health outcomes of female GW veterans independently.

Original languageEnglish (US)
Pages (from-to)610-616
Number of pages7
JournalJournal of occupational and environmental medicine
Volume61
Issue number7
DOIs
StatePublished - Jul 1 2019

Fingerprint

Gulf War
Veterans
Centers for Disease Control and Prevention (U.S.)
Sex Characteristics
Air

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Sex Differences in Gulf War Illness : A Reanalysis of Data From the CDC Air Force Study Using CDC and Modified Kansas Case Definitions. / Heboyan, Vahe; Krengel, Maxine H.; Sullivan, Kimberly; Iobst, Stacey; Klimas, Nancy; Wilson, Candy; Coughlin, Steven Scott.

In: Journal of occupational and environmental medicine, Vol. 61, No. 7, 01.07.2019, p. 610-616.

Research output: Contribution to journalArticle

@article{93bd6a80f7a546c18fee961ab0077549,
title = "Sex Differences in Gulf War Illness: A Reanalysis of Data From the CDC Air Force Study Using CDC and Modified Kansas Case Definitions",
abstract = "OBJECTIVE: Estimate and compare the prevalence of Gulf War Illness (GWI) in male and female Gulf War veterans using Centers for Disease Control and Prevention (CDC) and modified Kansas case definitions. METHODS: Data from the landmark CDC Air Force Study of GW Air Force veterans is used. RESULTS: Nearly half of the deployed veterans met the GWI CDC case definition compared with 14{\%} of non-deployed veterans. Only 29{\%} met the definition using the modified Kansas criteria compared with 8{\%} of non-deployed veterans. Deployed veterans and female veterans exhibited significantly higher GWI risk. Female GW veterans had higher rates of severe and mild-to-moderate cases of GWI. CONCLUSION: Results suggest increased GWI rates based on CDC and modified Kansas criteria among deployed and female veterans. Further research is needed to examine the chronic health outcomes of female GW veterans independently.",
author = "Vahe Heboyan and Krengel, {Maxine H.} and Kimberly Sullivan and Stacey Iobst and Nancy Klimas and Candy Wilson and Coughlin, {Steven Scott}",
year = "2019",
month = "7",
day = "1",
doi = "10.1097/JOM.0000000000001620",
language = "English (US)",
volume = "61",
pages = "610--616",
journal = "Journal of Occupational and Environmental Medicine",
issn = "1076-2752",
publisher = "Lippincott Williams and Wilkins",
number = "7",

}

TY - JOUR

T1 - Sex Differences in Gulf War Illness

T2 - A Reanalysis of Data From the CDC Air Force Study Using CDC and Modified Kansas Case Definitions

AU - Heboyan, Vahe

AU - Krengel, Maxine H.

AU - Sullivan, Kimberly

AU - Iobst, Stacey

AU - Klimas, Nancy

AU - Wilson, Candy

AU - Coughlin, Steven Scott

PY - 2019/7/1

Y1 - 2019/7/1

N2 - OBJECTIVE: Estimate and compare the prevalence of Gulf War Illness (GWI) in male and female Gulf War veterans using Centers for Disease Control and Prevention (CDC) and modified Kansas case definitions. METHODS: Data from the landmark CDC Air Force Study of GW Air Force veterans is used. RESULTS: Nearly half of the deployed veterans met the GWI CDC case definition compared with 14% of non-deployed veterans. Only 29% met the definition using the modified Kansas criteria compared with 8% of non-deployed veterans. Deployed veterans and female veterans exhibited significantly higher GWI risk. Female GW veterans had higher rates of severe and mild-to-moderate cases of GWI. CONCLUSION: Results suggest increased GWI rates based on CDC and modified Kansas criteria among deployed and female veterans. Further research is needed to examine the chronic health outcomes of female GW veterans independently.

AB - OBJECTIVE: Estimate and compare the prevalence of Gulf War Illness (GWI) in male and female Gulf War veterans using Centers for Disease Control and Prevention (CDC) and modified Kansas case definitions. METHODS: Data from the landmark CDC Air Force Study of GW Air Force veterans is used. RESULTS: Nearly half of the deployed veterans met the GWI CDC case definition compared with 14% of non-deployed veterans. Only 29% met the definition using the modified Kansas criteria compared with 8% of non-deployed veterans. Deployed veterans and female veterans exhibited significantly higher GWI risk. Female GW veterans had higher rates of severe and mild-to-moderate cases of GWI. CONCLUSION: Results suggest increased GWI rates based on CDC and modified Kansas criteria among deployed and female veterans. Further research is needed to examine the chronic health outcomes of female GW veterans independently.

UR - http://www.scopus.com/inward/record.url?scp=85069235569&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069235569&partnerID=8YFLogxK

U2 - 10.1097/JOM.0000000000001620

DO - 10.1097/JOM.0000000000001620

M3 - Article

VL - 61

SP - 610

EP - 616

JO - Journal of Occupational and Environmental Medicine

JF - Journal of Occupational and Environmental Medicine

SN - 1076-2752

IS - 7

ER -