Sex Differences in Hypertension: Recent Advances

Ellen E. Gillis, Jennifer C Sullivan

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Hypertension is a complex disorder involving multiple organ systems and the primary modifiable risk factor for heart disease, which is the leading cause of death among both men and women in the United States. Although both men and women develop hypertension, distinct gender differences in the incidence and severity of hypertension are well established where men have a higher incidence of hypertension compared with women of the same age until the sixth decade of life. Despite gender differences in human hypertension, the treatment guidelines do not differ by gender. The first goal of this review is to examine the clinical data to determine whether this is appropriate, with the remainder of the review focused on basic science research implicating a role for the immune system in mediating sex differences in hypertension.

Original languageEnglish (US)
Pages (from-to)1322-1327
Number of pages6
JournalHypertension
Volume68
Issue number6
DOIs
StatePublished - Dec 1 2016

Fingerprint

Sex Characteristics
Hypertension
Incidence
Cause of Death
Immune System
Heart Diseases
Guidelines
Research

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Sex Differences in Hypertension : Recent Advances. / Gillis, Ellen E.; Sullivan, Jennifer C.

In: Hypertension, Vol. 68, No. 6, 01.12.2016, p. 1322-1327.

Research output: Contribution to journalArticle

Gillis, Ellen E. ; Sullivan, Jennifer C. / Sex Differences in Hypertension : Recent Advances. In: Hypertension. 2016 ; Vol. 68, No. 6. pp. 1322-1327.
@article{795eae8b8fb747f095b1aed8b76f1766,
title = "Sex Differences in Hypertension: Recent Advances",
abstract = "Hypertension is a complex disorder involving multiple organ systems and the primary modifiable risk factor for heart disease, which is the leading cause of death among both men and women in the United States. Although both men and women develop hypertension, distinct gender differences in the incidence and severity of hypertension are well established where men have a higher incidence of hypertension compared with women of the same age until the sixth decade of life. Despite gender differences in human hypertension, the treatment guidelines do not differ by gender. The first goal of this review is to examine the clinical data to determine whether this is appropriate, with the remainder of the review focused on basic science research implicating a role for the immune system in mediating sex differences in hypertension.",
author = "Gillis, {Ellen E.} and Sullivan, {Jennifer C}",
year = "2016",
month = "12",
day = "1",
doi = "10.1161/HYPERTENSIONAHA.116.06602",
language = "English (US)",
volume = "68",
pages = "1322--1327",
journal = "Hypertension",
issn = "0194-911X",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Sex Differences in Hypertension

T2 - Recent Advances

AU - Gillis, Ellen E.

AU - Sullivan, Jennifer C

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Hypertension is a complex disorder involving multiple organ systems and the primary modifiable risk factor for heart disease, which is the leading cause of death among both men and women in the United States. Although both men and women develop hypertension, distinct gender differences in the incidence and severity of hypertension are well established where men have a higher incidence of hypertension compared with women of the same age until the sixth decade of life. Despite gender differences in human hypertension, the treatment guidelines do not differ by gender. The first goal of this review is to examine the clinical data to determine whether this is appropriate, with the remainder of the review focused on basic science research implicating a role for the immune system in mediating sex differences in hypertension.

AB - Hypertension is a complex disorder involving multiple organ systems and the primary modifiable risk factor for heart disease, which is the leading cause of death among both men and women in the United States. Although both men and women develop hypertension, distinct gender differences in the incidence and severity of hypertension are well established where men have a higher incidence of hypertension compared with women of the same age until the sixth decade of life. Despite gender differences in human hypertension, the treatment guidelines do not differ by gender. The first goal of this review is to examine the clinical data to determine whether this is appropriate, with the remainder of the review focused on basic science research implicating a role for the immune system in mediating sex differences in hypertension.

UR - http://www.scopus.com/inward/record.url?scp=84992390942&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84992390942&partnerID=8YFLogxK

U2 - 10.1161/HYPERTENSIONAHA.116.06602

DO - 10.1161/HYPERTENSIONAHA.116.06602

M3 - Article

C2 - 27777357

AN - SCOPUS:84992390942

VL - 68

SP - 1322

EP - 1327

JO - Hypertension

JF - Hypertension

SN - 0194-911X

IS - 6

ER -