SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders

Irene Litvan, Kailash P. Bhatia, David J. Burn, Christopher G. Goetz, Anthony E. Lang, Ian McKeith, Niall Quinn, Kapil Dev Sethi, Cliff Shults, Gregor K. Wenning

Research output: Contribution to journalReview article

714 Citations (Scopus)

Abstract

As there are no biological markers for the antemortem diagnosis of degenerative parkinsonian disorders, diagnosis currently relies upon the presence and progression of clinical features and confirmation depends on neuropathology. Clinicopathologic studies have shown significant false-positive and false-negative rates for diagnosing these disorders, and misdiagnosis is especially common during the early stages of these diseases. It is important to establish a set of widely accepted diagnostic criteria for these disorders that may be applied and reproduced in a blinded fashion. This review summarizes the findings of the SIC Task Force for the study of diagnostic criteria for parkinsonian disorders in the areas of Parkinson's disease, dementia with Lewy bodies, progressive supranuclear palsy, multiple system atrophy, and corticobasal degeneration. In each of these areas, diagnosis continues to rest on clinical findings and the judicious use of ancillary studies.

Original languageEnglish (US)
Pages (from-to)467-486
Number of pages20
JournalMovement Disorders
Volume18
Issue number5
DOIs
StatePublished - May 1 2003

Fingerprint

Parkinsonian Disorders
Advisory Committees
Progressive Supranuclear Palsy
Multiple System Atrophy
Lewy Body Disease
Diagnostic Errors
Parkinson Disease
Biomarkers

Keywords

  • Accuracy
  • Corticobasal degeneration
  • Dementia with Lewy bodies
  • Diagnostic criteria
  • Multiple system atrophy
  • Parkinson disease
  • Progressive supranuclear palsy
  • Reliability

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Litvan, I., Bhatia, K. P., Burn, D. J., Goetz, C. G., Lang, A. E., McKeith, I., ... Wenning, G. K. (2003). SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders. Movement Disorders, 18(5), 467-486. https://doi.org/10.1002/mds.10459

SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders. / Litvan, Irene; Bhatia, Kailash P.; Burn, David J.; Goetz, Christopher G.; Lang, Anthony E.; McKeith, Ian; Quinn, Niall; Sethi, Kapil Dev; Shults, Cliff; Wenning, Gregor K.

In: Movement Disorders, Vol. 18, No. 5, 01.05.2003, p. 467-486.

Research output: Contribution to journalReview article

Litvan, I, Bhatia, KP, Burn, DJ, Goetz, CG, Lang, AE, McKeith, I, Quinn, N, Sethi, KD, Shults, C & Wenning, GK 2003, 'SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders', Movement Disorders, vol. 18, no. 5, pp. 467-486. https://doi.org/10.1002/mds.10459
Litvan I, Bhatia KP, Burn DJ, Goetz CG, Lang AE, McKeith I et al. SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders. Movement Disorders. 2003 May 1;18(5):467-486. https://doi.org/10.1002/mds.10459
Litvan, Irene ; Bhatia, Kailash P. ; Burn, David J. ; Goetz, Christopher G. ; Lang, Anthony E. ; McKeith, Ian ; Quinn, Niall ; Sethi, Kapil Dev ; Shults, Cliff ; Wenning, Gregor K. / SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders. In: Movement Disorders. 2003 ; Vol. 18, No. 5. pp. 467-486.
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