Single flap approach with and without guided tissue regeneration and a hydroxyapatite biomaterial in the management of intraosseous periodontal defects

Leonardo Trombelli, Anna Simonelli, Mattia Pramstraller, Ulf M E Wikesjö, Roberto Farina

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

Background: The single flap approach (SFA) is aminimallyinvasive procedure designed for periodontal reconstructive procedures of intraosseous periodontal defects characterized bya dominant unilateral, buccal or oral, extension. This study evaluates the adjunctive effect of guided tissue regeneration(GTR) combined with a hydroxyapatite (HA) biomaterial in the management of intraosseous periodontal defects accessed with SFA compared to SFA alone. Methods: Twenty-four intraosseous defects (in 24 patients) were randomly allocated to treatmentwith SFA or SFA + HA/GTR. Clinical outcomes were assessed6 months postsurgery. Results: Five sites in the SFA + HA/GTRgroup showed incomplete closure at week 2, which resolved spontaneously. There were no statistically significant or clinicallymeaningful differences in mean (±SD) clinical attachment gain (4.7 ± 2.5 versus 4.4 ± 1.5 mm), probing depth reduction (5.3 ± 2.4 versus 5.3 ± 1.5 mm), and gingival recession increase (0.4 ± 1.4 versus 0.8 ± 0.8 mm) between the SFA + HA/GTR and SFA groups.Conclusions: SFA with and without HA/GTR seems to be a valuable minimally invasive approach in the treatment of deep intraosseous periodontal defects. Under the present experimental conditions, the additional HA/GTR protocol offers no significant adjunctive effect.

Original languageEnglish (US)
Pages (from-to)1256-1263
Number of pages8
JournalJournal of periodontology
Volume81
Issue number9
DOIs
StatePublished - Sep 1 2010

Keywords

  • Alveolar bone loss
  • Periodontitis
  • Reconstructive surgical procedures
  • Surgical flaps

ASJC Scopus subject areas

  • Periodontics

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