Site specific properties of carious dentin matrices biomodified with collagen cross-linkers

Ana K. Bedran-Russo, Sachin Karol, David Henry Pashley, Grace Viana

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: To assess in non-cavitated carious teeth the mechanical properties of dentin matrix by measuring its reduced modulus of elasticity and the effect of dentin biomodification strategies on three dentin matrix zones: caries-affected, apparently normal dentin below caries-affected zone and sound dentin far from carious site. Methods: Nano-indentations were performed on dentin matrices of carious molars before and after surface modification using known cross-linking agents (glutaraldehyde, proanthocyanidins from grape seed extract and carbodiimide). Results: Statistically significant differences were observed between dentin zones of demineralized dentin prior to surface biomodification (P< 0.05). Following surface modification, there were no statistically significant differences between dentin zones (P< 0.05). An average increase of 30-fold, 2-fold and 2.2-fold of the reduced modulus of elasticity was observed following treatments of the three dentin zones with proanthocyanidin, carbodiimide and glutaraldehyde, respectively.

Original languageEnglish (US)
Pages (from-to)244-248
Number of pages5
JournalAmerican journal of dentistry
Volume26
Issue number5
StatePublished - Oct 1 2013

Fingerprint

Dental Caries
Dentin
Collagen
Carbodiimides
Elastic Modulus
Glutaral
Grape Seed Extract
Proanthocyanidins
Tooth

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Bedran-Russo, A. K., Karol, S., Pashley, D. H., & Viana, G. (2013). Site specific properties of carious dentin matrices biomodified with collagen cross-linkers. American journal of dentistry, 26(5), 244-248.

Site specific properties of carious dentin matrices biomodified with collagen cross-linkers. / Bedran-Russo, Ana K.; Karol, Sachin; Pashley, David Henry; Viana, Grace.

In: American journal of dentistry, Vol. 26, No. 5, 01.10.2013, p. 244-248.

Research output: Contribution to journalArticle

Bedran-Russo, AK, Karol, S, Pashley, DH & Viana, G 2013, 'Site specific properties of carious dentin matrices biomodified with collagen cross-linkers', American journal of dentistry, vol. 26, no. 5, pp. 244-248.
Bedran-Russo, Ana K. ; Karol, Sachin ; Pashley, David Henry ; Viana, Grace. / Site specific properties of carious dentin matrices biomodified with collagen cross-linkers. In: American journal of dentistry. 2013 ; Vol. 26, No. 5. pp. 244-248.
@article{902876ad7f064781959459040b6b782a,
title = "Site specific properties of carious dentin matrices biomodified with collagen cross-linkers",
abstract = "Purpose: To assess in non-cavitated carious teeth the mechanical properties of dentin matrix by measuring its reduced modulus of elasticity and the effect of dentin biomodification strategies on three dentin matrix zones: caries-affected, apparently normal dentin below caries-affected zone and sound dentin far from carious site. Methods: Nano-indentations were performed on dentin matrices of carious molars before and after surface modification using known cross-linking agents (glutaraldehyde, proanthocyanidins from grape seed extract and carbodiimide). Results: Statistically significant differences were observed between dentin zones of demineralized dentin prior to surface biomodification (P< 0.05). Following surface modification, there were no statistically significant differences between dentin zones (P< 0.05). An average increase of 30-fold, 2-fold and 2.2-fold of the reduced modulus of elasticity was observed following treatments of the three dentin zones with proanthocyanidin, carbodiimide and glutaraldehyde, respectively.",
author = "Bedran-Russo, {Ana K.} and Sachin Karol and Pashley, {David Henry} and Grace Viana",
year = "2013",
month = "10",
day = "1",
language = "English (US)",
volume = "26",
pages = "244--248",
journal = "American Journal of Dentistry",
issn = "0894-8275",
publisher = "Mosher and Linder, Inc",
number = "5",

}

TY - JOUR

T1 - Site specific properties of carious dentin matrices biomodified with collagen cross-linkers

AU - Bedran-Russo, Ana K.

AU - Karol, Sachin

AU - Pashley, David Henry

AU - Viana, Grace

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Purpose: To assess in non-cavitated carious teeth the mechanical properties of dentin matrix by measuring its reduced modulus of elasticity and the effect of dentin biomodification strategies on three dentin matrix zones: caries-affected, apparently normal dentin below caries-affected zone and sound dentin far from carious site. Methods: Nano-indentations were performed on dentin matrices of carious molars before and after surface modification using known cross-linking agents (glutaraldehyde, proanthocyanidins from grape seed extract and carbodiimide). Results: Statistically significant differences were observed between dentin zones of demineralized dentin prior to surface biomodification (P< 0.05). Following surface modification, there were no statistically significant differences between dentin zones (P< 0.05). An average increase of 30-fold, 2-fold and 2.2-fold of the reduced modulus of elasticity was observed following treatments of the three dentin zones with proanthocyanidin, carbodiimide and glutaraldehyde, respectively.

AB - Purpose: To assess in non-cavitated carious teeth the mechanical properties of dentin matrix by measuring its reduced modulus of elasticity and the effect of dentin biomodification strategies on three dentin matrix zones: caries-affected, apparently normal dentin below caries-affected zone and sound dentin far from carious site. Methods: Nano-indentations were performed on dentin matrices of carious molars before and after surface modification using known cross-linking agents (glutaraldehyde, proanthocyanidins from grape seed extract and carbodiimide). Results: Statistically significant differences were observed between dentin zones of demineralized dentin prior to surface biomodification (P< 0.05). Following surface modification, there were no statistically significant differences between dentin zones (P< 0.05). An average increase of 30-fold, 2-fold and 2.2-fold of the reduced modulus of elasticity was observed following treatments of the three dentin zones with proanthocyanidin, carbodiimide and glutaraldehyde, respectively.

UR - http://www.scopus.com/inward/record.url?scp=84889852097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889852097&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84889852097

VL - 26

SP - 244

EP - 248

JO - American Journal of Dentistry

JF - American Journal of Dentistry

SN - 0894-8275

IS - 5

ER -