Sleep disturbances and substance use disorders: A bi-directional relationship

Anjum Ara, William Solomon Jacobs, Ishrat Ali Bhat, William Vaughn McCall

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

A complex bi-directional relationship exists between substance use and sleep that encompasses several sleep disturbances including insomnia, hypersomnia, obstructive sleep apnea, and excessive daytime sleepiness. Substances of abuse produce their effect by acting on various receptor and neurotransmitter systems, some of which are involved in normal sleep regulation. Disruption of these neurotransmitter systems can lead to changes in the normal sleep architecture, causing sleep disturbances. Sleep disturbances can persist even after abstinence, a fact that is often not well recognized by substance use disorder treatment programs, and can lead to relapses. Incorporating strategies to counter sleep disturbances can help in relapse prevention. Pharmacologic and nonpharmacologic strategies exist that can be used to treat sleep disturbances in substance use disorders. The potential scope of these strategies is large, but currently there are limited data regarding which pharmacologic options are effective in treating sleep disturbances in patients with substance use disorders. Further advancement in the development of pharmacologic agents could lead to new strategies to help in relapse prevention and successful completion of substance use disorder treatment programs. This review explores the complex bi-directional relationship between substance use and sleep disturbances.

Original languageEnglish (US)
Pages (from-to)408-412
Number of pages5
JournalPsychiatric Annals
Volume46
Issue number7
DOIs
StatePublished - Jul 1 2016

Fingerprint

Substance-Related Disorders
Sleep
Secondary Prevention
Disorders of Excessive Somnolence
Neurotransmitter Receptor
Sleep Initiation and Maintenance Disorders
Obstructive Sleep Apnea
Neurotransmitter Agents
Recurrence
Therapeutics

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Sleep disturbances and substance use disorders : A bi-directional relationship. / Ara, Anjum; Jacobs, William Solomon; Bhat, Ishrat Ali; McCall, William Vaughn.

In: Psychiatric Annals, Vol. 46, No. 7, 01.07.2016, p. 408-412.

Research output: Contribution to journalReview article

Ara, Anjum ; Jacobs, William Solomon ; Bhat, Ishrat Ali ; McCall, William Vaughn. / Sleep disturbances and substance use disorders : A bi-directional relationship. In: Psychiatric Annals. 2016 ; Vol. 46, No. 7. pp. 408-412.
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