Smooth muscle Insulin-like growth factor-1 mediates hypoxia-induced pulmonary hypertension in neonatal mice

Medicine & Life Sciences

• Somatomedins 100%
• Pulmonary Hypertension 93%
• Smooth Muscle 82%
• Hypoxia 74%
• 3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol 53%
• Vascular Remodeling 33%
• Vascular Smooth Muscle 27%
• Lung 25%
• Smooth Muscle Myocytes 24%
• mouse insulin-like growth factor-1 17%
• Right Ventricular Hypertrophy 12%
• Somatomedin Receptors 12%
• Ventricular Pressure 10%
• Mitogens 9%
• Arteries 6%
• Up-Regulation 6%
• Age Groups 6%
• Blood Pressure 5%
• Therapeutics 3%

Chemical Compounds

• Mitogen 14%
• Proliferative 13%
• Pressure 6%