Sooty foot, a novel mouse mutation that affects the pigmentation of exposed skin, but not hair, maps to Chromosome 2

Peter S. Budd, Jane Antoniou, Andrew L. Mellor, Ian J. Jackson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We have characterized a novel recessive mouse mutation, named sooty foot, that increases the pigmentation of the exposed skin on the foot pads, the genital region, around the snout and muzzle, the ears, and the tail. By contrast, the pigmentation of the hair is unaffected. We have localized the mutation to Chromosome 2 by polymerase chain reaction (PCR) amplification of simple sequence repeats from pooled DNA from backcross progeny. In an extended backcross we have generated a detailed map of the region around sooty foot.

Original languageEnglish (US)
Pages (from-to)631-635
Number of pages5
JournalMammalian Genome
Volume8
Issue number9
DOIs
StatePublished - Sep 1 1997

Fingerprint

Skin Pigmentation
Chromosomes, Human, Pair 2
Hair
Foot
Mutation
Pigmentation
Microsatellite Repeats
Ear
Tail
Polymerase Chain Reaction
DNA

ASJC Scopus subject areas

  • Genetics

Cite this

Sooty foot, a novel mouse mutation that affects the pigmentation of exposed skin, but not hair, maps to Chromosome 2. / Budd, Peter S.; Antoniou, Jane; Mellor, Andrew L.; Jackson, Ian J.

In: Mammalian Genome, Vol. 8, No. 9, 01.09.1997, p. 631-635.

Research output: Contribution to journalArticle

Budd, Peter S. ; Antoniou, Jane ; Mellor, Andrew L. ; Jackson, Ian J. / Sooty foot, a novel mouse mutation that affects the pigmentation of exposed skin, but not hair, maps to Chromosome 2. In: Mammalian Genome. 1997 ; Vol. 8, No. 9. pp. 631-635.
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