Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling

Brian Kirkpatrick, Linh Nguyen, Galina Kondrikova, Samuel Herberg, William D. Hill

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Stromal-derived factor 1-alpha (SDF-1α, or CXCL12α) is a major chemokine that controls adult stem cell trafficking. Little is known about its stability after blood sampling, but this is a crucial issue for clinical studies of this molecule. In a study of six subjects, we found total human plasma SDF-1α concentrations to be stable for 120 min when the blood is placed on ice immediately after sampling.

Original languageEnglish (US)
Pages (from-to)257-260
Number of pages4
JournalAnnals of Clinical and Laboratory Science
Volume40
Issue number3
StatePublished - Jun 1 2010

Fingerprint

Blood
Sampling
Plasma (human)
Adult Stem Cells
Ice
Stem cells
Chemokines
Molecules
Clinical Studies

Keywords

  • Chemokines
  • CXCL12α
  • Stromal-derived factor-1α

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology

Cite this

Kirkpatrick, B., Nguyen, L., Kondrikova, G., Herberg, S., & Hill, W. D. (2010). Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling. Annals of Clinical and Laboratory Science, 40(3), 257-260.

Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling. / Kirkpatrick, Brian; Nguyen, Linh; Kondrikova, Galina; Herberg, Samuel; Hill, William D.

In: Annals of Clinical and Laboratory Science, Vol. 40, No. 3, 01.06.2010, p. 257-260.

Research output: Contribution to journalArticle

Kirkpatrick, B, Nguyen, L, Kondrikova, G, Herberg, S & Hill, WD 2010, 'Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling', Annals of Clinical and Laboratory Science, vol. 40, no. 3, pp. 257-260.
Kirkpatrick B, Nguyen L, Kondrikova G, Herberg S, Hill WD. Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling. Annals of Clinical and Laboratory Science. 2010 Jun 1;40(3):257-260.
Kirkpatrick, Brian ; Nguyen, Linh ; Kondrikova, Galina ; Herberg, Samuel ; Hill, William D. / Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling. In: Annals of Clinical and Laboratory Science. 2010 ; Vol. 40, No. 3. pp. 257-260.
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