Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling

Brian Kirkpatrick, Linh Nguyen, Galina Kondrikova, Samuel Herberg, William D. Hill

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Stromal-derived factor 1-alpha (SDF-1α, or CXCL12α) is a major chemokine that controls adult stem cell trafficking. Little is known about its stability after blood sampling, but this is a crucial issue for clinical studies of this molecule. In a study of six subjects, we found total human plasma SDF-1α concentrations to be stable for 120 min when the blood is placed on ice immediately after sampling.

Original languageEnglish (US)
Pages (from-to)257-260
Number of pages4
JournalAnnals of Clinical and Laboratory Science
Volume40
Issue number3
StatePublished - Jun 1 2010

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Keywords

  • CXCL12α
  • Chemokines
  • Stromal-derived factor-1α

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology

Cite this

Kirkpatrick, B., Nguyen, L., Kondrikova, G., Herberg, S., & Hill, W. D. (2010). Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling. Annals of Clinical and Laboratory Science, 40(3), 257-260.