State of the art etch-and-rinse adhesives

David Henry Pashley, Franklin Chi Meng Tay, Lorenzo Breschi, Leo Tjäderhane, Ricardo M. Carvalho, Marcela Carrilho, Arzu Tezvergil-Mutluay

Research output: Contribution to journalArticle

435 Citations (Scopus)

Abstract

Objectives: The aim of this study was to explore the therapeutic opportunities of each step of 3-step etch-and-rinse adhesives. Methods: Etch-and-rinse adhesive systems are the oldest of the multi-generation evolution of resin bonding systems. In the 3-step version, they involve acid-etching, priming and application of a separate adhesive. Each step can accomplish multiple goals. Acid-etching, using 32-37% phosphoric acid (pH 0.1-0.4) not only simultaneously etches enamel and dentin, but the low pH kills many residual bacteria. Results: Some etchants include anti-microbial compounds such as benzalkonium chloride that also inhibits matrix metalloproteinases (MMPs) in dentin. Primers are usually water and HEMA-rich solutions that ensure complete expansion of the collagen fibril meshwork and wet the collagen with hydrophilic monomers. However, water alone can re-expand dried dentin and can also serve as a vehicle for protease inhibitors or protein cross-linking agents that may increase the durability of resin-dentin bonds. In the future, ethanol or other water-free solvents may serve as dehydrating primers that may also contain antibacterial quaternary ammonium methacrylates to inhibit dentin MMPs and increase the durability of resin-dentin bonds. The complete evaporation of solvents is nearly impossible. Significance: Manufacturers may need to optimize solvent concentrations. Solvent-free adhesives can seal resin-dentin interfaces with hydrophobic resins that may also contain fluoride and antimicrobial compounds. Etch-and-rinse adhesives produce higher resin-dentin bonds that are more durable than most 1 and 2-step adhesives. Incorporation of protease inhibitors in etchants and/or cross-linking agents in primers may increase the durability of resin-dentin bonds. The therapeutic potential of etch-and-rinse adhesives has yet to be fully exploited.

Original languageEnglish (US)
Pages (from-to)1-16
Number of pages16
JournalDental Materials
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2011

Fingerprint

Dentin
Adhesives
Resins
Durability
Protease Inhibitors
Matrix Metalloproteinases
Collagen
Water
Etching
Benzalkonium Compounds
Acids
Methacrylates
Enamels
Phosphoric acid
Fluorides
Ammonium Compounds
Seals
Bacteria
Evaporation
Dental Enamel

Keywords

  • Acid-etchants
  • Adhesives
  • Durability
  • MMPs
  • Primers

ASJC Scopus subject areas

  • Materials Science(all)
  • Dentistry(all)
  • Mechanics of Materials

Cite this

Pashley, D. H., Tay, F. C. M., Breschi, L., Tjäderhane, L., Carvalho, R. M., Carrilho, M., & Tezvergil-Mutluay, A. (2011). State of the art etch-and-rinse adhesives. Dental Materials, 27(1), 1-16. https://doi.org/10.1016/j.dental.2010.10.016

State of the art etch-and-rinse adhesives. / Pashley, David Henry; Tay, Franklin Chi Meng; Breschi, Lorenzo; Tjäderhane, Leo; Carvalho, Ricardo M.; Carrilho, Marcela; Tezvergil-Mutluay, Arzu.

In: Dental Materials, Vol. 27, No. 1, 01.01.2011, p. 1-16.

Research output: Contribution to journalArticle

Pashley, DH, Tay, FCM, Breschi, L, Tjäderhane, L, Carvalho, RM, Carrilho, M & Tezvergil-Mutluay, A 2011, 'State of the art etch-and-rinse adhesives', Dental Materials, vol. 27, no. 1, pp. 1-16. https://doi.org/10.1016/j.dental.2010.10.016
Pashley DH, Tay FCM, Breschi L, Tjäderhane L, Carvalho RM, Carrilho M et al. State of the art etch-and-rinse adhesives. Dental Materials. 2011 Jan 1;27(1):1-16. https://doi.org/10.1016/j.dental.2010.10.016
Pashley, David Henry ; Tay, Franklin Chi Meng ; Breschi, Lorenzo ; Tjäderhane, Leo ; Carvalho, Ricardo M. ; Carrilho, Marcela ; Tezvergil-Mutluay, Arzu. / State of the art etch-and-rinse adhesives. In: Dental Materials. 2011 ; Vol. 27, No. 1. pp. 1-16.
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