Stereotactic radiosurgery of malignant and benign intracranial lesions utilizing a patient rotator

Cargill Herley Alleyne, Tim H. Fox, Jeffrey J. Olson, George A. Cotsonis, Ian Crocker, Roy A.E. Bakay

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This study examines the characteristics of the patient groups, treatment parameters, and results of therapy for 126 intracranial lesions treated with stereotactic radiosurgery utilizing a 'patient rotator' and a linear accelerator. A retrospective review was conducted and data on 122 patients (21 patients with arteriovenous malformations-AVMs, 40 patients with 41 metastatic tumors, 24 patients with malignant gliomas and 37 patients with other benign lesions) were analyzed. Clinical and radiographic response was obtained from chart review and/or telephone follow-up. The average follow-up was 12.1, 13.0, 5.7, and 23.1 months in patients with AVMs, malignant gliomas, metastases, and other lesions, respectively. Median survival times (MST) of the metastatic and glioma groups were 9 and 38 months, respectively. Complete or partial radiographic response at follow-up was seen in 62.5% of AVM patients, 33.3% of patients with metastases, 11.8% of patients with malignant gliomas, and 19.3% of patients with other lesions. (1) Local control of brain metastases and benign intracranial lesions can be obtained with single dose stereotactic radiosurgery. (2) The MST and local control rate for metastatic disease obtained are comparable with those in the literature. (3) The patient rotator method for stereotactic radiosurgery is an effective tool for treating selected intracranial lesions.

Original languageEnglish (US)
Pages (from-to)20-30
Number of pages11
JournalRadiation Oncology Investigations
Volume5
Issue number1
DOIs
StatePublished - Jul 1 1997

Fingerprint

Radiosurgery
lesions
Glioma
metastasis
Neoplasm Metastasis
telephones
Particle Accelerators
Survival
linear accelerators
charts
Arteriovenous Malformations
Telephone
brain
therapy
tumors

Keywords

  • Arteriovenous malformation
  • Brain neoplasm
  • Linear accelerator
  • Radiosurgery
  • Stereotactic radiosurgery

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Stereotactic radiosurgery of malignant and benign intracranial lesions utilizing a patient rotator. / Alleyne, Cargill Herley; Fox, Tim H.; Olson, Jeffrey J.; Cotsonis, George A.; Crocker, Ian; Bakay, Roy A.E.

In: Radiation Oncology Investigations, Vol. 5, No. 1, 01.07.1997, p. 20-30.

Research output: Contribution to journalArticle

Alleyne, Cargill Herley ; Fox, Tim H. ; Olson, Jeffrey J. ; Cotsonis, George A. ; Crocker, Ian ; Bakay, Roy A.E. / Stereotactic radiosurgery of malignant and benign intracranial lesions utilizing a patient rotator. In: Radiation Oncology Investigations. 1997 ; Vol. 5, No. 1. pp. 20-30.
@article{a1b04f0cdcae49cdab3bc4921381f58c,
title = "Stereotactic radiosurgery of malignant and benign intracranial lesions utilizing a patient rotator",
abstract = "This study examines the characteristics of the patient groups, treatment parameters, and results of therapy for 126 intracranial lesions treated with stereotactic radiosurgery utilizing a 'patient rotator' and a linear accelerator. A retrospective review was conducted and data on 122 patients (21 patients with arteriovenous malformations-AVMs, 40 patients with 41 metastatic tumors, 24 patients with malignant gliomas and 37 patients with other benign lesions) were analyzed. Clinical and radiographic response was obtained from chart review and/or telephone follow-up. The average follow-up was 12.1, 13.0, 5.7, and 23.1 months in patients with AVMs, malignant gliomas, metastases, and other lesions, respectively. Median survival times (MST) of the metastatic and glioma groups were 9 and 38 months, respectively. Complete or partial radiographic response at follow-up was seen in 62.5{\%} of AVM patients, 33.3{\%} of patients with metastases, 11.8{\%} of patients with malignant gliomas, and 19.3{\%} of patients with other lesions. (1) Local control of brain metastases and benign intracranial lesions can be obtained with single dose stereotactic radiosurgery. (2) The MST and local control rate for metastatic disease obtained are comparable with those in the literature. (3) The patient rotator method for stereotactic radiosurgery is an effective tool for treating selected intracranial lesions.",
keywords = "Arteriovenous malformation, Brain neoplasm, Linear accelerator, Radiosurgery, Stereotactic radiosurgery",
author = "Alleyne, {Cargill Herley} and Fox, {Tim H.} and Olson, {Jeffrey J.} and Cotsonis, {George A.} and Ian Crocker and Bakay, {Roy A.E.}",
year = "1997",
month = "7",
day = "1",
doi = "10.1002/(SICI)1520-6823(1997)5:1<20::AID-ROI4>3.0.CO;2-M",
language = "English (US)",
volume = "5",
pages = "20--30",
journal = "Radiation Oncology Investigations",
issn = "1065-7541",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

TY - JOUR

T1 - Stereotactic radiosurgery of malignant and benign intracranial lesions utilizing a patient rotator

AU - Alleyne, Cargill Herley

AU - Fox, Tim H.

AU - Olson, Jeffrey J.

AU - Cotsonis, George A.

AU - Crocker, Ian

AU - Bakay, Roy A.E.

PY - 1997/7/1

Y1 - 1997/7/1

N2 - This study examines the characteristics of the patient groups, treatment parameters, and results of therapy for 126 intracranial lesions treated with stereotactic radiosurgery utilizing a 'patient rotator' and a linear accelerator. A retrospective review was conducted and data on 122 patients (21 patients with arteriovenous malformations-AVMs, 40 patients with 41 metastatic tumors, 24 patients with malignant gliomas and 37 patients with other benign lesions) were analyzed. Clinical and radiographic response was obtained from chart review and/or telephone follow-up. The average follow-up was 12.1, 13.0, 5.7, and 23.1 months in patients with AVMs, malignant gliomas, metastases, and other lesions, respectively. Median survival times (MST) of the metastatic and glioma groups were 9 and 38 months, respectively. Complete or partial radiographic response at follow-up was seen in 62.5% of AVM patients, 33.3% of patients with metastases, 11.8% of patients with malignant gliomas, and 19.3% of patients with other lesions. (1) Local control of brain metastases and benign intracranial lesions can be obtained with single dose stereotactic radiosurgery. (2) The MST and local control rate for metastatic disease obtained are comparable with those in the literature. (3) The patient rotator method for stereotactic radiosurgery is an effective tool for treating selected intracranial lesions.

AB - This study examines the characteristics of the patient groups, treatment parameters, and results of therapy for 126 intracranial lesions treated with stereotactic radiosurgery utilizing a 'patient rotator' and a linear accelerator. A retrospective review was conducted and data on 122 patients (21 patients with arteriovenous malformations-AVMs, 40 patients with 41 metastatic tumors, 24 patients with malignant gliomas and 37 patients with other benign lesions) were analyzed. Clinical and radiographic response was obtained from chart review and/or telephone follow-up. The average follow-up was 12.1, 13.0, 5.7, and 23.1 months in patients with AVMs, malignant gliomas, metastases, and other lesions, respectively. Median survival times (MST) of the metastatic and glioma groups were 9 and 38 months, respectively. Complete or partial radiographic response at follow-up was seen in 62.5% of AVM patients, 33.3% of patients with metastases, 11.8% of patients with malignant gliomas, and 19.3% of patients with other lesions. (1) Local control of brain metastases and benign intracranial lesions can be obtained with single dose stereotactic radiosurgery. (2) The MST and local control rate for metastatic disease obtained are comparable with those in the literature. (3) The patient rotator method for stereotactic radiosurgery is an effective tool for treating selected intracranial lesions.

KW - Arteriovenous malformation

KW - Brain neoplasm

KW - Linear accelerator

KW - Radiosurgery

KW - Stereotactic radiosurgery

UR - http://www.scopus.com/inward/record.url?scp=12644317833&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=12644317833&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1520-6823(1997)5:1<20::AID-ROI4>3.0.CO;2-M

DO - 10.1002/(SICI)1520-6823(1997)5:1<20::AID-ROI4>3.0.CO;2-M

M3 - Article

C2 - 9303053

AN - SCOPUS:12644317833

VL - 5

SP - 20

EP - 30

JO - Radiation Oncology Investigations

JF - Radiation Oncology Investigations

SN - 1065-7541

IS - 1

ER -